Non-invasive transcranial ultrasound blood pressure measurement device and method based on sonovue

Abstract

The invention discloses a SonoVue-based non-invasive transcranial ultrasonic blood pressure measurement device and method, which includes a skull bionic module, a blood circulation pressurization system and a pressure measurement unit. The blood circulation pressurization system is connected, and SonoVue microbubble solution is injected into the blood vessel phantom to run instead of blood, and the pressure of the blood vessel phantom is controlled through the blood circulation pressurization system, and the arbitrary waveform generator and ultrasonic probe are used to emit different waves to the skull phantom. The incident sound pressure and the pressure of the blood-light phantom are controlled at the same time, and then the relationship between different incident sound pressures, the acoustic scattering signal of the vascular phantom and the pressure of the vascular phantom is obtained, and then the intracranial blood pressure is determined according to the relationship between the three. Realize convenient intracranial pressure measurement, reflect the relationship between intracranial blood pressure and injection boost, make the relationship between SonoVue sub-harmonic amplitude and hydrostatic pressure present the optimal linear relationship, not only realize accurate and non-invasive measurement of intracranial Blood pressure, the relationship between intracranial blood pressure and intracranial pressure can also be studied.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a SonoVue-based non-invasive transcranial ultrasound blood pressure measurement device and method. Background technique [0002] At present, stroke has become a major disease that plagues the health of modern people, and the common cerebral artery and large blood vessel occlusion is the most common and malignant. The middle cerebral artery is an intermediate link in the closed loop of the brain. For people with normal operation of the middle cerebral artery, the blood pressure of the middle cerebral artery is basically equal to the mean arterial pressure of the whole body. When the middle cerebral artery or common internal carotid artery is narrowed or blocked, the middle cerebral artery The blood pressure is much lower than the mean arterial pressure, which shows that the monitoring of middle cerebral artery pressure can be used as a screening method for middle cerebral artery occ...

AI Technical Summary

Problems solved by technology

[0005] Aiming at the problem that SonoVue cannot realize pressure measurement in the prior art, the present invention provides a non-invasive transcranial ultrasonic blood pressure measurement device and method based on SonoVue coated microbubbles, so that the relationship between SonoVue sub-harmonic amplitude and hydrostatic pressure Presenting the optimal linear relationship, not only to achieve accurate non-invasive measurement of intracranial blood pressure, but also to study the relationship between intracranial blood pressure and intracranial pressure

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