Safe and non-toxic dyeing and perming agent, preparation method and application

A safe, non-toxic, dyeing and perming agent technology, used in pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of damage to the keratin of hair scales, light color of dyed hair, and low color adhesion, and achieve good results. UV shielding effect, increased washing fastness, effect of protecting damaged hair

Active Publication Date: 2021-04-13
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its strong alkaline environment will destroy the keratin of the hair scales, and it can only be dyed its own brown color instead of darker black, and the color adhesion is low
Mimicking Natural Human Hair Pigmentation with Synthetic Melanin, ACSCentral Science 2020 6(7), 1179-1188 mentioned the use of CuSO 4 +H 2 o 2 The Fenton-like system promotes the synthesis of melanin for hair dyeing, but there are still shortcomings such as lighter hair color, too single color, and metal ions
And there is still no dyeing and perming agent for hair dyeing and perm simultaneously on the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Preparation of agent A1: add ammonium thioglycolate, oleyl polyether, cocamidopropyl betaine, and add ethanolamine to adjust the pH to 9. The concentration of ammonium thioglycolate in the A1 agent reaches 16wt%, the concentration of oleyl polyether in the A1 agent reaches 1wt%, and the content of cocamidopropyl betaine in the A1 agent is 0.5wt%.

[0033] Preparation of agent A2: add cystine into Tris buffer solution with pH 8.5, stir until dissolved. Add dopamine hydrochloride, mix it with agent A1 at a ratio of 1:1 after stirring, and use it. The content of cystine in A2 agent is 0.5 mg / mL, and the content of dopamine hydrochloride is 1 mg / mL.

[0034] Preparation of agent B: add sodium bromate, and add an appropriate amount of hair conditioning agent laurylamine oxide. The content of sodium bromate in agent B is 8%wt, and the content of laurylamine oxide is 0.5wt%.

[0035] Preparation of agent C: add the thickener Pluronic F127 and the surfactant cocamidopropyl b...

Embodiment 2

[0038] The specific implementation process is the same as in Example 1, wherein the cystine content in the A2 dose is changed to 0.2 mg / mL.

Embodiment 3

[0040] The specific implementation process is the same as in Example 1, wherein the content of dopamine hydrochloride in the A2 dose is changed to 2 mg / mL.

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PUM

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Abstract

The invention provides a safe and non-toxic dyeing and perming agent, a preparation method and application, and belongs to the field of special cosmetics. The dyeing and perming agent is a melanin dyeing and perming agent integrating dyeing and perming, and comprises an agent A1, an agent A2, an agent B and an agent C, wherein the agent A1 is a mercaptoacetic acid, mercaptoacetate or cysteine reducing agent solution; the agent A2 comprises cystine or a derivative thereof, a buffer solution and a melanin precursor substance; the agent B is sodium bromate or a hydrogen peroxide type oxidizing agent solution; and the agent C comprises a melanin precursor substance, a buffer solution and an oxidizing agent. The melanin precursor substance is used for dyeing hair, and phenylenediamine substances with high carcinogenic and sensitization risks are avoided. The hair dyeing process is combined with the perming process, dyeing and perming are integrated, and secondary damage to hair due to the fact that perming is conducted before dyeing is not needed. Melanin is attached to the surface of hair, has a good ultraviolet shielding effect, can protect hair keratin against yellowing and embrittlement caused by ultraviolet rays, and protects damaged hair.

Description

technical field [0001] The invention belongs to the field of special cosmetics, and in particular relates to a synthetic melanin dyeing and ironing agent combined with dyeing and ironing and its application. Background technique [0002] Most people begin to decline from the age of 35, and the hair pigment cells begin to decline, and gray hair appears gradually. The population structure of today's society is gradually aging, and the demand for green and healthy hair dyes will also increase. However, all hair dyes currently on the market contain phenylenediamine substances, which are highly carcinogenic and sensitizing risk. Hairdressers may be at an increased risk of cancer due to frequent exposure to hair dye and other chemicals, according to the World Health Organization's International Agency for Research on Cancer. [0003] Polydopamine is a kind of natural melanin with excellent biocompatibility. Using polydopamine instead of phenylenediamine as the black precursor o...

Claims

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Application Information

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IPC IPC(8): A61K8/20A61K8/22A61K8/41A61K8/44A61K8/46A61K8/49A61K8/64A61K8/66A61Q5/00A61Q5/06A61Q5/10
CPCA61K8/20A61K8/22A61K8/41A61K8/447A61K8/46A61K8/492A61K8/64A61K8/66A61Q5/004A61Q5/06A61Q5/10
Inventor 东为富郑宸李婷汪洋张正陈明清马丕明
Owner JIANGNAN UNIV
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