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Dairy cow feed additive as well as preparation method and application thereof

A dairy cow feed and additive technology, applied in application, animal feed, animal feed, etc., can solve the problems of extensive drug resistance and antibiotic residues in dairy cow milk, improve milk production and milk quality of dairy cows, and maintain hormone homeostasis , the effect of improving the structure

Pending Publication Date: 2021-04-16
INNER MONGOLIA AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of this, the present invention provides a dairy cow feed additive and its preparation method and application, which can solve the problems of extensive drug resistance and antibiotic residues in milk cow milk caused by the use of drug feed additives in existing dairy cows to prevent and treat cow mastitis and other diseases

Method used

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  • Dairy cow feed additive as well as preparation method and application thereof
  • Dairy cow feed additive as well as preparation method and application thereof
  • Dairy cow feed additive as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0038] Embodiment: the preparation of dairy cattle feed additive

[0039] 1. Preparation of curcumin and turmeric volatile oil

[0040] (1) Preparation of turmeric volatile oil: smash turmeric through an 80-mesh sieve, soak turmeric in distilled water at room temperature for 24 hours, and extract by steam distillation. When the distillate is clear and transparent, stop distillation and dry for about 6 hours.

[0041] (2) Preparation of curcumin: adopt 95% ethanol to extract turmeric, 1.5h / time, 3 times; Filter, the extract is filtered into the storage tank through 120 mesh stainless steel mesh, merge three filtrates; Concentrate; Carry out with 95% ethanol Alcohol precipitation, duration: 12h, temperature: 10°C; recover ethanol;

[0042] 2. After mixing turmeric volatile oil and curcumin in a weight ratio of 1:10, add auxiliary materials (dextrin and sucrose), the purity of turmeric volatile oil and curcumin is 75%, and collect paste; granulate; dry and sieve; sterilize; Pac...

experiment example

[0044] Experimental example: Specifically explain the impact of dairy cow feed additives on the immune ability of dairy cows:

[0045] 1 Antibacterial protection rate test of curcumin and Bacillus subtilis in mice

[0046] 1.1 Test material

[0047] 1.1.1 Test reagents

[0048] Turmeric was purchased from Inner Mongolia Tianli Pharmaceutical Co., Ltd.; nutrient agar medium and nutrient broth medium were purchased from Guangdong Huankai Microbiology Co., Ltd.; ethanol was purchased from Shandong Fengcang Chemical Co., Ltd.; DMSO (dimethyl sulfoxide ), purchased from Beijing Kulaiboke Co., Ltd.

[0049] 1.1.2 Test strains

[0050] The strain of Bacillus subtilis (CMCCB62501) was purchased from the Wuhan Miaoling plasmid platform; the pathogenic S.aureus was provided by the Cattle Production Laboratory of the College of Animal Science, Inner Mongolia Agricultural University, from the No. It is isolated from the milk of Holstein cows with mastitis, and is separated, purified, id...

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Abstract

The invention discloses a dairy cow feed additive as well as a preparation method and an application thereof, the dairy cow feed additive comprises curcumin, turmeric volatile oil and bacillus subtilis, and the concentration of the bacillus subtilis is 1 * 10<7> cfu / mL to 1*10<12>cfu / mL; the additive solves the problems of wide drug resistance and dairy cow milk antibiotic residue caused by prevention and treatment of dairy cow mastitis and other diseases by using the existing dairy cow medicinal feed additive.

Description

technical field [0001] The invention relates to a mixed feed additive, in particular to a feed additive for regulating the immune function of dairy cows. Background technique [0002] At present, in the dairy farming industry, dairy cow mastitis still seriously affects the health and economic benefits of dairy cows. Long-term extensive use of antibiotics to treat dairy cow mastitis will directly lead to widespread drug resistance of bacteria, antibiotic residues in cow milk, and seriously affect human health. And in the field of animal breeding, growth-promoting drug feed additives have been completely banned, antibiotics are banned in feed, and it is imperative to reduce antibiotics in breeding. Contents of the invention [0003] In view of this, the present invention provides a dairy cow feed additive and its preparation method and application, which solves the problems of extensive drug resistance and antibiotic residues in milk cow milk caused by the use of drug feed ...

Claims

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Application Information

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IPC IPC(8): A23K50/10A23K10/30A23K20/111A23K10/18A01K67/02
Inventor 王纯洁张琨敖日格乐郭振双徐进张欣
Owner INNER MONGOLIA AGRICULTURAL UNIVERSITY
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