Super-capacity information coding system and application thereof

A technology of information coding and coding system, applied in Raman scattering, material excitation analysis, etc., can solve the problems of Raman signal stability deterioration, limited information coding capacity, and inaccurate decoded information, etc., to achieve good signal stability , Improve decoding efficiency, easy to decode

Pending Publication Date: 2021-04-20
HUAZHONG NORMAL UNIV
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  • Description
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AI Technical Summary

Problems solved by technology

However, whether it is the signal peak of the commonly used signal molecules in the fingerprint region using surface-enhanced Raman, or the spontaneous Raman signal peak of the triple-bond compound in the silent region, the current bottleneck in obtaining a large-capacity encoding system is still: because the strategy adopted is When the nanoparticle or triple bond compound used for surface enhancement is physically adsorbed onto the microsphere, it is difficult to accurately control the signal intensity loaded on the medium carrier when the types of Raman signal molecules, that is, the types of characteristic Raman signal frequencies, are continuously increased. proportion
Moreover, the Raman signal on the carrier may interfere with the detection reaction in the subsequent multiple detection process, resulting in poor stability of the Raman signal and inaccurate decoded information.
Therefore, the encoding unit of the signal strength at the same frequency can only realize ternary (0, 1, 2) at most, which greatly limits the capacity of information encoding

Method used

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  • Super-capacity information coding system and application thereof
  • Super-capacity information coding system and application thereof
  • Super-capacity information coding system and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1. Establishment of super-large-capacity coding system

[0059] (1) Establishment of Raman signal molecule library

[0060] Taking 28 representative Raman signal molecules, their Raman shifts are divided into 4 spectral bands, namely the I, II, III and IV bands. The structural formulas and Raman spectra of 28 compounds are shown in figure 2 shown. Divide 28 kinds of compounds into (a) group and (b) group respectively, such as figure 2 (a) and figure 2 (b).

[0061] figure 2 (a) Group compounds are as follows from left to right:

[0062]

[0063] figure 2 (b) Group compounds are as follows from left to right:

[0064]

[0065] (2) Octal coding unit on the surface carrier

[0066] First, through a simple mixing strategy in solution, we combine figure 2 A of the I band in a (2100cm -1 ) and A’(2109cm -1 ), B of the second band (2134cm -1 ) and B’(2138cm -1 ), C (2168cm -1 ) and C’(2180cm -1 ) and D (2209cm -1 ) and D’(2223cm -1 ), mak...

Embodiment 2

[0071] Example 2. Example of information coding system encoding both ASCII and Unicode data

[0072] The octal encoding unit is written on the quartz glass in the form of wet ink and dry ink, realizing the encoding of two data storage systems, ASCII and Unicode. For example, using figure 2 A(2100cm) of band I in (a) -1 ) and D of Band IV (2209cm -1) / D'(2223cm -1 ) to encode the ASCII (American Standard Code for Information Interchange) system. ASCII is an 8-bit binary system where each code represents a unique character. The ASCII code has a total of 128 codes, including the first 32 non-printing control characters and the remaining 96 printing characters. Correspondingly, we prepared 128 Raman codes. Firstly, stock solutions of the normalized coding units of A, D, D' and R were prepared, and the solvent was N-methylpyrrolidone, and the concentrations thereof were 2.6M, 0.10M, 0.27M and 0.25M, respectively. Then prepare the storage solution of the octal coding unit, a...

Embodiment 3

[0075] Example 3. Using this method to encode resin beads and its use in high-throughput screening of polypeptide ligands for special cancer cells

[0076] First prepare the compound and (Chemical structure see figure 2 ) of the normalized coding unit activation reaction solution, specifically and Mix with equivalent 6-chloro-1-hydroxybenzotriazole (Cl-HOBt) and N,N'-diisopropylcarbodiimide (DIC) in N,N-dimethylformamide solvent in, get and The concentrations are 0.132M, 0.0033M, 0.0060M, 0.010M and 0.052M, respectively. the aforementioned stock solution and respectively with The mixing volume ratio is 0, 0.30, 0.45, 0.68, 1.01, 1.52, 2.28, 3.42, and the activation reaction solution of the respective octal coding units can be obtained and When the octal code that needs to be designed is multi-digit, the corresponding storage solution of the above volume ratio and Combination mixing is carried out to obtain the desired coding solution. For example,...

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Abstract

The invention discloses a super-capacity information coding system and application thereof. The system comprises an encoding system and a decoding system which are formed by combining encoding units loaded on an encoding carrier, and a multi-system encoding unit for realizing the intensity at the same wavelength by adjusting a plurality of spontaneous Raman scattering intensities of a triple-bond compound, raman signal molecules are subjected to combined mixing in different proportions in a solution and then dropwise added to a two-dimensional planar carrier or covalently bonded to a three-dimensional resin bead carrier, and the loading process is uniform and controllable.

Description

technical field [0001] The invention belongs to the technical field of chemical analysis methods, and in particular relates to a super-capacity information coding system and its application. Background technique [0002] The combination of optical coding technology and multiplexing technology makes it develop rapidly. With the emergence of lasers, luminescent materials, and high-resolution microscopy, opportunities are provided for the discovery of new optical encoding systems carrying multiple information, which greatly improves the throughput of biometric identification and scientific and technological discovery. Such an optical encoding system needs to meet several key requirements: (1) explore new optical dimensions for information encoding; (2) produce high-throughput information encoding systems; (3) develop a decoding instrument platform for information retrieval ; (4) Provide system compatibility that matches specific applications. In order to improve the encoding ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65
Inventor 高婷娟唐浴尘贺彩丽
Owner HUAZHONG NORMAL UNIV
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