Method for determining various components in chest-broadening aerosol based on GC-MS/MS

Abstract

The invention discloses a method for determining various components in a wide chest aerosol based on GCMS / MS. According to the method, the contents of 12 components which comprises eucalyptol, isoborneol, borneol, methyl eugenol, elemicin, alpha pinene, sweet myrrh terpene alcohol, beta pinene, L-camphor, caryophyllene, alpha humulene and trans-nerolidol in the wide chest aerosol are simultaneously determined by adopting GCMS / MS. In order to remove the matrix effect and the influence of instrument states in different time periods on the sensitivity, an internal standard solution is also added into the test solution, and the determination method is simple, high in instrument precision, good in solution stability, high in determination result accuracy and good in method reproducibility. The determination method provided by the invention can be used for carrying out comprehensive quantitative analysis on the chest-broadening aerosol and providing technical support for better exerting the curative effect of the chest-broadening aerosol.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine quality detection, in particular to a GC-MS / MS-based method for measuring various components in Kuanxiong aerosol. Background technique [0002] Kuanxiong aerosol is composed of 5 herbs including sandalwood oil, galangal oil, asarum oil, longan oil, and borneol. Chest paralysis caused. Kuanxiong aerosol is a traditional Chinese medicine aerosol developed on the basis of the theory of "aroma and warming" that is "replenishment by tonic and main tonic". It is an effective prescription for quick-acting pain relief in the treatment of coronary heart disease and angina pectoris. The main component of Kuanxiong aerosol is volatile oil, which is distributed in a molecular state. It can be quickly absorbed into the blood by the human body, expand coronary vessels, significantly improve myocardial ischemia, and quickly relieve chest tightness, chest pain, palpitations, shortness of br...

AI Technical Summary

Problems solved by technology

This patent application is actually the determination of the characteristic spectrum of sandalwood oil in the wide chest aerosol, which can well reflect the sandalwood oil components in the wide chest aerosol, but there is no way to get the exact content of each component of the sandalwood oil, let alone Get a full checkup on Wide Chest Aerosol

Therefore, so far, there is no method for comprehensive detection of wide-breasted aerosols accurately and quickly.

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