Naphthalene derivative fluorescent probe as well as preparation method and application thereof

Abstract

The invention discloses a naphthalene derivative fluorescent probe as well as a preparation method and application thereof, and relates to a fluorescent detection probe as well as a preparation method and application thereof. In order to solve the technical problems that no fluorescent probe for relay fluorescence detection of Hg < 2 + > and I <-> in an aqueous solution exists at present and the probe is easily influenced by Au < 3 + >, Fe < 2 + > and Fe < 3 + >, the naphthalene derivative fluorescent probe is 1-benzyl-3-(1-naphthylamine acetyl) benzimidazole chloride, the structural formula is shown in the specification, and the naphthalene derivative fluorescent probe is prepared through N-alkylation, amidation and quaternization reactions. The fluorescent probe and Hg < 2 + > form a stable complex, so that fluorescence is enhanced to detect the Hg < 2 + >; the detection can be carried out in a pH value range of 7.0-11.0, and the detection limit reaches 9.7 * 10 <-8 > mol / L; and in addition, the complex N-Hg < 2 + > can recover fluorescence after I <-> is added to realize I <-> detection, and the probe can be used in the fields of environmental science, analytical chemistry, life science and medicine.

Description

technical field [0001] The invention relates to a fluorescent detection probe, a preparation method and application thereof. Background technique [0002] Due to the development of industry and agriculture, a large number of heavy metal ions have entered the human ecological environment, which has caused a series of health and environmental problems. In the 1950s, the Minamata disease broke out in Japan. Since then, the pollution of mercury ions has attracted worldwide attention. Mercury ions bioaccumulate under the action of the food chain, and finally enter the human body through food, water, etc., and are absorbed by the human body. , will cause damage to the central nervous system and endocrine system of the human body, leading to various diseases. At the same time, iodide ion is also an indispensable trace element in the human body, but excessive intake of iodide ion may increase the incidence of thyroid cancer. Therefore, how to detect Hg in aqueous solution 2+ and I...

AI Technical Summary

Problems solved by technology

[0004] The present invention is to solve the problem that currently there is no relay fluorescence detection of Hg in aqueous solution. 2+ and I – Fluorescent probes and probes susceptible to Au 3+ , Fe 2+ and Fe 3+ Influenced technical problems, and provide a kind of fluorescent probe of naphthalene derivatives and its preparation method and application, this probe can detect Hg in aqueous solution with high selectivity relay fluorescence 2+ and I –

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