The present application relates to treating and / or preventing
breast cancer, including
locally advanced or metastatic, ER+, HER2-
breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), N n R2 N N O HO ON R R4 NH O (R1) m (I), or a pharmaceutically acceptable salt,
enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or
prodrug thereof, wherein R¹, R², R3, R4, m, and n are defined herein. 20 26 20 54 21 08 J ul 2 02 6 0 8 J u l 2 0 2 6 A B S T R A C T 2 0 2 6 2 0 5 4 2 1 N n N N O H O O N R R 4 N H O m