Electroactive antibacterial healing-promoting catheter and preparation method thereof

An electroactive and urinary catheter technology, applied in the direction of catheters, electrotherapy, and other medical devices, can solve the problems of not being able to enhance the endogenous physiological electric field and promote wound healing

Active Publication Date: 2021-07-06
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above-mentioned patents can only achieve antibacterial effect. When the urinary catheter is used in postoperative patients of

Method used

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  • Electroactive antibacterial healing-promoting catheter and preparation method thereof
  • Electroactive antibacterial healing-promoting catheter and preparation method thereof

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[0028] The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.

[0029] Such as figure 1 , 2As shown, an electroactive antibacterial promoter uterus comprises a body portion 1 for insertion into the human body, the surface of the body is formed into a rough surface of a plurality of trenches and pits after the plasma etching 4, The sputtering of the rough surface 4 is composed of the electrode layer A and the electrode layer B to form an electrochemical discharge after contact with the leakage urine, physiological saline or wound oozing liquid, the electrode layer A2 and The pitch of the electrode layer B3 ranges from 0.5 mm to 6.5 mm. The roughness of the rough surface is 150 nm-500 nm, facilitating the electrolytic solution 5 to keep the antibacterial impaired layer and the rough surface to ensure electrochemical discharge, so that the catheter surface It has a more comprehensive antibacterial and inhibits the...

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Abstract

The invention relates to the technical field of medical care, in particular to an electroactive antibacterial healing-promoting catheter and a preparation method thereof.The electroactive antibacterial healing-promoting catheter comprises a body part used for being inserted into a human body, wherein the surface of the body part is etched through plasma to form a rough surface with a plurality of grooves and pits, an antibacterial healing-promoting layer composed of an electrode layer A and an electrode layer B is sputtered on the rough surface, the distance between the electrode layer A and the electrode layer B ranges from 0.5 mm to 6.5 mm, the roughness of the rough surface ranges from 150 nm to 500 nm, the roughness of the antibacterial healing-promoting layer ranges from 20 nm to 250 nm, and the thickness of the antibacterial healing-promoting layer ranges from 10 nm to 500 nm. The catheter can generate electrochemical discharge after being in contact with leaked urine, normal saline, tissue fluid or wound exudate and the like, has responsive discharge property and has good sterilization and biological membrane inhibition effects, and the antibacterial healing-promoting layer has relatively good uniformity, does not influence the flexibility, elasticity, lubricity and the like of the catheter, and the antibacterial healing-promoting layer is firmly combined with the catheter.

Description

Technical field [0001] The present invention relates to the field of healthcare technologies, in particular, an electroactive antibacterial tohability catheter and a preparation method thereof. Background technique [0002] Urinary tract infection (UTI) is a very common medical infection in today's healthcare system. UTI hospital stays, high cost, and extra risk in the health of patients. UTI is usually related to the installation of urine catheters. Through clinical studies have shown that the catheter keeps an increase of approximately 10% UTI risks per day. Bacteria enters (about 64%) from the outside or from the interior (about 36%). Most microbial infections are caused by a biofilm that may be formed on various surfaces. In addition to urinary tract infections, the biofilm may also cause various other infections, such as blood infections. Blood infection in the form of vessel may have serious consequences. [0003] Medical catheter is consumed from several hours to several d...

Claims

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Application Information

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IPC IPC(8): A61M25/00A61N1/18A61L29/08
CPCA61M25/0045A61N1/18A61L29/126A61M2025/0056A61M2025/0058A61M2207/00
Inventor 李纪伟张少华董海斌王娜马建伟陈韶娟
Owner QINGDAO UNIV
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