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Biomechanical loading device based on hard material

A biomechanical, loading device technology, applied in biochemical cleaning devices, enzymology/microbiology devices, biochemical equipment and methods, etc., can solve the limitations of the generalization of research results, and cannot well simulate the mechanical environment of bone tissue, etc. question

Pending Publication Date: 2021-07-23
SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, most of the traditional biomechanical research uses the Flexcell system, which is completed by seeding cells on the flexible basement membrane and applying tensile or compressive stress to the basement membrane. This research mode cannot well simulate the bone tissue with high stiffness. Mechanical environment, thus limiting the generalization significance of its research results

Method used

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  • Biomechanical loading device based on hard material
  • Biomechanical loading device based on hard material
  • Biomechanical loading device based on hard material

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Embodiment Construction

[0027] In order to enable those skilled in the art to better understand the technical solution of the present invention, its specific implementation will be described in detail below in conjunction with the accompanying drawings:

[0028] see figure 1 , figure 2 , image 3 and Figure 4 , the best embodiment of the present invention, a biomechanical loading device based on hard materials, including a controller (not shown in the figure), a drive mechanism and an actuator, the drive mechanism and the actuator are arranged on the substrate 1, wherein:

[0029] The executive mechanism includes a push-down lever 2 and a booster auxiliary container 3; the push-down lever 2 includes a lever 21, a connection frame 22, a support seat 23 and a bracket 24, the lever 21 is arranged horizontally, and one end of the lever 21 is inserted and fixed in the connection frame 22 , the other end of the lever 21 is provided with a fixed point 41 on the wire rope; the support seat 23, the auxil...

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Abstract

The invention discloses a biomechanical loading device based on a hard material. The biomechanical loading device comprises a controller, a driving mechanism and an executing mechanism; the driving mechanism and the executing mechanism are arranged on a substrate; the executing mechanism comprises a pressing lever and a stress application auxiliary container; the pressing lever comprises a lever, a connecting frame, a supporting seat and a bracket; two connectors are arranged at the bottom end of the connecting frame; one connector is connected with the supporting seat through a rotating shaft, and the other connector is in contact with the top end of the stress application auxiliary container; the driving mechanism comprises a motor driving chip, a motor encoder and a motor; the motor encoder is respectively communicated with the motor driving chip and the motor; and the controller is communicated with the motor driving chip. According to the biomechanical loading device based on the hard material, which is disclosed by the invention, exploration on the biomechanical properties of implant surface cells can be implemented by adopting a specific metal or alloy material, and the in-vivo high-rigidity bone tissue mechanical environment can be well simulated.

Description

technical field [0001] The invention relates to a biomechanical loading device based on hard materials. Background technique [0002] Bone tissue is a mechanically loaded organ that supports the human body, so bone tissue is always in a complex biomechanical environment. Bone cells such as osteoblasts and chondrocytes have the ability to respond to biomechanical stimuli, and biomechanical signals in daily life can regulate the biological functions of various types of bone cells. Lack of effective mechanical stimulation can lead to imbalances in bone metabolism. For example, astronauts who have been in space for a long time in a weightless environment will experience significant bone loss in their weight-bearing bones. It can be seen that maintaining mechanical stimulation plays an important role in bone balance. In order to better explore the relationship between mechanical stimulation and bone tissue, it is necessary to clarify the biomechanical response mechanism of bone...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/36C12M1/00
CPCC12M25/14C12M35/04C12M41/48
Inventor 李慧武常永云童志成夏润之胡弋孔柯瑜
Owner SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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