Brain injury marker analysis system based on DTI and serum factors

Abstract

The invention relates to a brain injury marker analysis system based on diffusion tensor imaging (DTI) and a serum factor, the system comprises a DTI scanning module, a serum detection module and a data processing module, and the system is controlled according to the following modes: firstly, detecting the serum inflammatory factor level of venous blood extracted from an empty stomach by adopting an enzyme-linked immunosorbent assay; then, carrying out DTI scanning, carrying out image processing and data analysis on the collected images, and obtaining change data of the FA and the ADC; normalizing a serum inflammatory factor level parameter and an FA value and an ADC value obtained by magnetic resonance diffusion imaging by using a least square method, then defining a sign function, and taking a result of the sign function as a reference for a doctor to analyze and formulate a next detection scheme.

Description

technical field [0001] The invention belongs to the medical field, in particular to a brain injury marker analysis system based on DTI (Diffusion Tensor Imaging, diffusion tensor imaging) and serum factors. Background technique [0002] With the development of society, people's lives are gradually improving, and people's lifestyles have also undergone great changes. For example, the development of transportation has brought us great convenience, but many traffic accidents have also occurred, which has improved the Chance of traumatic brain injury. Craniocerebral injury is an acute injury to the brain, sometimes due to external violence such as traffic accidents and mechanical trauma. The condition of craniocerebral injury develops and changes rapidly. If the patient cannot be diagnosed and treated in time, the prognosis will be poor and will seriously affect the patient's physical and mental health and even life. Studies have shown that mild traumatic brain injury accounts ...

AI Technical Summary

Problems solved by technology

[0003] The main pathological change in patients with MTBI is hemorrhage, and most of the hemorrhages that occur in MTBI are intracranial microbleeds. At present, CT examination and conventional MRI are mainly used, but minor brain injuries may not be found in all neuroimaging examinations. lesions, this is because the current neuroimaging technology has not been able to distinguish some small structures and lesions

Moreover, CT and conventional MRI can only show the anatomical changes of brain tissue, which has great limitations in the diagnosis of MTBI, etc., and often misses the diagnosis or underestimates the severity of traumatic brain injury.

In addition to CT and conventional MRI, there are other diagnostic methods for minor brain injury, mainly including neurological function test, physical examination and medical history, but these methods are not very convenient and not very accurate

MR Diffusion Tensor Imaging (DTI) is a new MRI scanning technology that has been used clinically in recent years to describe the diffusion direction of water molecules. It can quantitatively evaluate the movement of water molecules in brain tissue. rate is still relatively high

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