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Traditional Chinese medicine composition for treating rash and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating skin rash, can solve the problems of dry skin, affecting the quality of life of patients, affecting the curative effect and the like

Inactive Publication Date: 2021-09-07
北京市中医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Skin toxicity is the most common adverse reaction, mainly manifested as acne-like rash, pruritus, dry skin, etc., which seriously affects the quality of life of patients, and in some cases, the drug needs to be stopped, affecting the curative effect

Method used

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  • Traditional Chinese medicine composition for treating rash and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Grind purslane, green prickly ash, atractylodes, parsnip, mirabilite, alum, forsythia, raw arborvitae leaves, and scallion into fine powder, sieve and set aside.

[0033] According to the ratio of 15 parts of purslane, 9 parts of green pepper, 9 parts of Atractylodes, 9 parts of windproof, 30 parts of Glauber's salt, 10 parts of alum, 15 parts of forsythia, 9 parts of raw arborvitae leaves and 5 parts of scallion white, mix well. Then mix it with Vaseline in a mass ratio of 1:4 to make an ointment.

Embodiment 2

[0035] Grind purslane, green prickly ash, atractylodes, parsnip, mirabilite, alum, forsythia, raw arborvitae leaves, and scallion into fine powder, sieve and set aside.

[0036] According to the ratio of 18 parts of purslane, 8 parts of green pepper, 6 parts of Atractylodes, 11 parts of windproof, 32 parts of Glauber's salt, 8 parts of alum, 16 parts of forsythia, 8 parts of raw arborvitae leaves and 5 parts of light blue, mix well, Then mix it with Vaseline in a mass ratio of 1:4 to make an ointment.

Embodiment 3

[0038] Grind purslane, green prickly ash, atractylodes, parsnip, mirabilite, alum, forsythia, raw arborvitae leaves, and scallion into fine powder, sieve and set aside.

[0039] Mix well according to the ratio of 12 parts of purslane, 10 parts of green pepper, 12 parts of Atractylodes Rhizoma, 7 parts of Fangfeng, 28 parts of Glauber's salt, 12 parts of alum, 14 parts of Forsythia suspensa, 10 parts of raw arborvitae leaves and 5 parts of scallion white, Then mix it with Vaseline in a mass ratio of 1:4 to make an ointment.

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Abstract

The invention provides a traditional Chinese medicine composition for treating rash and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 12 to 18 parts of herba portulacae, 8 to 10 parts of green prickleyash, 6 to 12 parts of rhizoma atractylodis, 7 to 11 parts of radix saposhnikoviae, 28 to 32 parts of mirabilite, 8 to 12 parts of alum, 14 to 16 parts of fructus forsythiae, 8 to 10 parts of raw cacumen biotae and 3 to 7 parts of fistular onion stalk.The traditional Chinese medicine composition disclosed by the invention is simple and convenient in preparation process and has a good effect of treating rash caused by cetuximab.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating skin rash and application thereof. Background technique [0002] Cetuximab is an IgG1 monoclonal antibody against the EGF receptor. After the specific binding of the two, it blocks the intracellular signal transduction pathway by inhibiting the tyrosine kinase (TK) binding to the EGF receptor. , thereby inhibiting the proliferation of cancer cells, inducing apoptosis of cancer cells, reducing the production of matrix metalloproteinases and vascular endothelial growth factor. As a selective epidermal growth factor receptor monoclonal antibody for injection, cetuximab is widely used in a variety of solid tumors due to its cytotoxicity and molecular targeting, including metastatic colorectal cancer, non-small cell Lung cancer and squamous cell carcinoma of the head and neck. With the widespread use of cet...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61K9/06A61K47/06A61P17/00A61K33/04A61K33/06
CPCA61K36/185A61K36/758A61K36/284A61K36/238A61K33/04A61K33/06A61K36/634A61K36/14A61K36/8962A61K9/06A61K47/06A61P17/00A61K2300/00
Inventor 王圆圆张青赵文硕李颖吴霞刘敏
Owner 北京市中医研究所
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