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Traditional Chinese medicine composition for preventing and/or treating decayed teeth as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of oral care, can solve the problems of high extraction process requirements, complex and few traditional Chinese medicine ingredients, etc.

Inactive Publication Date: 2021-09-14
QINGDAO STOMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the complex ingredients of traditional Chinese medicine and the high requirements of the extraction process, it is impossible to obtain a stable and effective extract that can prevent dental caries, and because the special taste of Chinese herbal medicine ingredients will affect the color and smell of toothpaste, mouthwash and other products, so it can be applied at present. There are not many traditional Chinese medicine compositions for the prevention and treatment of dental caries

Method used

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  • Traditional Chinese medicine composition for preventing and/or treating decayed teeth as well as preparation method and application thereof
  • Traditional Chinese medicine composition for preventing and/or treating decayed teeth as well as preparation method and application thereof
  • Traditional Chinese medicine composition for preventing and/or treating decayed teeth as well as preparation method and application thereof

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preparation example Construction

[0022] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising the following steps: mixing licorice, honeysuckle, magnolia bark and an ethanol solution with a volume fraction of 70%-90%, refluxing extraction, and concentrating under reduced pressure until the relative density is 1.25-1.5, to obtain material 1; mix Galla, cloves, and bitter ginseng with water, soak, decoct 1-3 times, and concentrate under reduced pressure to a relative density of 1.15-1.2 to obtain material 2; mix material 1 and material 2, that is Obtain the Chinese medicine composition.

[0023] In the preparation method of the present invention, each medicinal raw material is subjected to alcohol extraction or water advance, and preferably all need to be pulverized. The present invention has no special limitation on the specific method of pulverization, and conventional pulverization methods in the field can be used. In the present...

Embodiment 1

[0029] 20g of licorice, 60g of honeysuckle and 30g of Magnolia officinalis were crushed and passed through a 100-mesh sieve to obtain a mixed powder. The mixed powder was mixed with 330g of ethanol solution with a volume fraction of 70%, extracted twice at 80°C under reflux, and the extract was collected and concentrated under reduced pressure When the relative density is 1.25 (measured at 20°C), material 1 is obtained; crush 40g gallnut, 50g clove and 80g flavescens and pass through a 100-mesh sieve to obtain a mixed powder, mix the mixed powder with 340g water, soak for 2 hours, and decoct Twice, concentrate under reduced pressure to a relative density of 1.15 (measured at 20°C) to obtain material 2; mix material 1 and material 2 to obtain a traditional Chinese medicine composition.

Embodiment 2

[0031]80g of licorice, 120g of honeysuckle and 90g of Magnolia officinalis were crushed and passed through a 80-mesh sieve to obtain a mixed powder, which was mixed with 680g of ethanol solution with a volume fraction of 85%, refluxed at 90°C for 4 times, and the extract was collected and concentrated under reduced pressure When the relative density is 1.5 (measured at 20°C), material 1 is obtained; crush 80g gallnut, 100g clove and 200g sophora flavescens and pass through an 80-mesh sieve to obtain a mixed powder, mix the mixed powder with 1900g water, soak for 5 hours, and decoct 3 times, concentrated under reduced pressure to a relative density of 1.15 (measured at 20° C.) to obtain material 2; mix material 1 and material 2 to obtain a traditional Chinese medicine composition.

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Abstract

The invention provides a traditional Chinese medicine composition for preventing and / or treating decayed teeth as well as a preparation method and application thereof, and belongs to the technical field of oral care. The traditional Chinese medicine composition for preventing and / or treating decayed teeth, provided by the invention, is prepared from the following raw materials in parts by weight of 20 to 80 parts of liquorice root, 60 to 120 parts of flos lonicerae, 30 to 90 parts of cortex magnoliae officinalis, 40 to 80 parts of Chinese gall, 50 to 100 parts of clove and 80 to 200 parts of radix sophorae flavescentis. The traditional Chinese medicine composition provided by the invention can be used for stably and effectively preventing and treating decayed teeth, integrally adjusting oral microorganism balance, improving oral health environment, inhibiting growth and adhesion of cariogenic bacteria and realizing remineralization, so that the occurrence and development of the decayed teeth are fundamentally prevented and treated.

Description

technical field [0001] The invention belongs to the technical field of oral care, and in particular relates to a traditional Chinese medicine composition for preventing and / or treating dental caries, a preparation method and application thereof. Background technique [0002] Dental caries, commonly known as caries and tooth decay, is a bacterial disease that can be secondary to pulpitis and apical periodontitis, and can even cause alveolar bone and jaw inflammation. If not treated in time, the lesion will continue to develop, forming cavities, and eventually the crown will be completely destroyed and disappeared. Untreated cavities will not heal on their own and the end result of their development is tooth loss. Dental caries is a progressive lesion of dental hard tissue caused by a combination of factors in the oral cavity, manifested as demineralization of inorganic matter and decomposition of organic matter. It is characterized by high incidence and wide distribution. ...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P1/02A61K8/98A61K8/9789A61Q11/00A61K35/64
CPCA61K36/484A61K36/355A61K36/575A61K35/64A61K36/61A61K36/489A61P1/02A61K8/987A61K8/9789A61Q11/00A61K2236/333A61K2236/51A61K2236/331A61K2236/39A61K2300/00
Inventor 李杰
Owner QINGDAO STOMATOLOGICAL HOSPITAL
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