Postbiotic compound, preparation method and application thereof in resisting helicobacter pylori and gastrointestinal diseases

Abstract

The invention provides a postbiotic compound. The postbiotic compound comprises bean powder, inactivated probiotics and metabolites of the inactivated probiotics, the compound has the advantages that 1, the slow release effect of inactivated probiotics and metabolites thereof can be realized; 2, helicobacter pylori in the body can be effectively removed, and stomach discomfort caused by helicobacter pylori can be relieved, such as stomachache, heartburn, gastric acid, gastric ulcer and the like; 3, the acting time is long, and the acting area is large; and 4, the problems existing in the storage and transportation processes of the viable bacteria are solved. Meanwhile, the invention also provides a preparation method and application of the compound.

Description

technical field [0001] The invention relates to a postbiotic compound, in particular to a compound capable of combating Helicobacter pylori and adjuvant treatment of stomach-related diseases. Background technique [0002] Helicobacter pylori (Hp) is a helical or S-shaped, microaerophilic, Gram-negative bacillus belonging to the order Campylobacteriaceae, the family Helicobacteriaceae, and the genus Helicobacter. The infection is specific and often settles on the gastric mucosal surface. Because there are several unipolar sheathed flagella at its end, it can quickly escape the acidic environment in the gastric cavity, and then pass through the thick mucus layer to reach and colonize the surface of the gastric mucosa. Helicobacter pylori infection is the cause of upper gastrointestinal diseases such as chronic gastritis, peptic ulcer, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. According to epidemiological surveys, more than half of the wor...

AI Technical Summary

Problems solved by technology

However, in general, probiotics have the following disadvantages: 1. The storage period of probiotics is short and the storage environment is harsh; The impact of the environment and antibacterial ingredients has caused the number of viable bacteria to be greatly reduced when the probiotics reach the gastrointestinal tract, and it is impossible to achieve a good probiotic effect

[0005] Therefore, in the treatment of anti-Helicobacter pylori, there is an urgent need for an alternative that does not produce side effects like antibiotics, and can solve the problems of low utilization rate of probiotics and difficulty in preservation.

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