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I-type collagen suspension medicament and preparation method thereof

A collagen, type I technology, applied in the field of collagen, can solve the problems of obvious injection pain, embolism, overfullness, etc., and achieve the effect of simple and easy to control the preparation process, brighten the skin color, and enhance the elasticity

Inactive Publication Date: 2021-10-01
常慧楠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The concentration of the existing type I collagen on the market is generally 30-35mg / mL, which has the function of slightly filling the volume, but the single-component type I collagen is not suitable for full-face penetrating large-dose injections, because it will produce excessive fullness. situation occurs, and there is a risk of embolism due to high concentrations
In addition, the existing type I collagen does not contain anesthetic ingredients, and the injection pain is extremely obvious
[0003] There is another type III collagen on the market, but its concentration is too low to stimulate collagen production to a limited extent, and its preparation is a transparent preparation, which does not have the effect of skin whitening

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The present embodiment provides a preparation method of a type I collagen suspension agent, specifically:

[0029] Take 1mL of Shuangmeiroumei (concentration of 30mg / mL), and add 0.5mL of vitamin B respectively 12 (concentration of 0.25 mg / mL), 1 mL of normal saline, 0.5 mL of lidocaine (concentration of 0.02 g / mL), double-pass repeated bolus injection 80 times to obtain the type I collagen suspension.

Embodiment 2

[0031] The present embodiment provides a preparation method of a type I collagen suspension agent, specifically:

[0032] Take 2mL of collagen type I (concentration of 30mg / mL), and add 0.5mL of vitamin B respectively 12 (concentration is 0.25 mg / mL), 2 mL of normal saline, 0.5 mL of anesthetic, double-pass repeated bolus injection 75 times to obtain the type I collagen suspension.

Embodiment 3

[0034] The present embodiment provides a preparation method of a type I collagen suspension agent, specifically:

[0035] Take 1mL of collagen type I (concentration of 30mg / mL), and add 0.75mL of vitamin B respectively 12 (concentration is 0.25 mg / mL), 1 mL of normal saline, 0.75 mL of anesthetic, double-pass repeated bolus injection 75 times to obtain the type I collagen suspension.

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Abstract

The invention relates to an I-type collagen suspension medicament and a preparation method thereof. The I-type collagen suspension medicament is prepared from the following raw materials: I-type collagen, vitamin B12, normal saline and anesthetic. The components of the I-type collagen suspension medicament are scientifically compatible, and the I-type collagen suspension medicament is an ultra-fine structure suspension which is not easy to cause embolism and sufficient in effective concentration, and particularly has a good diffusion effect on tissues lacking collagen due to aging around an injection position. After being in contact with collagen, each layer of soft tissue can be woven into a mesh and enter an original collagen fiber mesh, so that part of original tissue structure positions and functions are recovered, and finally, the face is young. Comprehensively, the subcutaneous fat chamber can be reset, and the elasticity of the ligament can be recovered; the skin is bright in color and enhanced in elasticity; the face deep fat pad is elastic and three-dimensional, and finally the whole face is in a full, young, smooth and gully-free state; the preparation process is simple and easy to control, and large-scale production is facilitated.

Description

technical field [0001] The invention belongs to the technical field of collagen, in particular to a type I collagen suspension agent and a preparation method thereof. Background technique [0002] The concentration of type I collagen on the market is generally 30-35mg / mL, which has the function of slightly filling the volume, but the single-component type I collagen is not suitable for high-dose injection throughout the whole body, because it will produce excessively full. situation occurs and there is a risk of embolism due to high concentrations. In addition, the existing type I collagen does not contain anesthesia ingredients, and the injection pain is extremely obvious. [0003] There is another type of collagen type III on the market, but its concentration is too low to stimulate the production of collagen, and its preparation is a transparent preparation, which does not have a skin-whitening effect. [0004] Therefore, based on this, the technical solution of the pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61K9/10A61K47/02A61P17/16A61P17/18A61K31/167A61K31/714
CPCA61K38/39A61K31/714A61K31/167A61K9/10A61K47/02A61K9/0019A61P17/18A61P17/16A61K2300/00
Inventor 常慧楠
Owner 常慧楠
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