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Traditional Chinese medicine microneedle transdermal delivery patch and preparation method thereof

A transdermal drug delivery and microneedle technology, applied in the field of biomedicine, can solve the problems of ineffective swelling and pain relief, and can not be cured, and achieve the effect of reducing medical cost burden, reducing pain and significant curative effect

Inactive Publication Date: 2021-11-12
河南佳普医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Any traditional Chinese medicine plaster currently on the market for the treatment of Lao Sui and shoulder, neck, waist, and leg pain can only temporarily relieve the pain of the patient, and the effect of reducing swelling and pain is not obvious, and cannot be cured

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] According to a kind of traditional Chinese medicine microneedle transdermal drug delivery patch according to the present invention, the raw materials of the plaster are: 4 parts of small bark bone, 4 parts of Moutan cortex, 7 parts of peony seed oil, 2 parts of Angelica sinensis, 5 parts of Aconitum aconitum , 3 parts of Atractylodes atractylodes, 4 parts of Achyranthes bidentata, 4 parts of myrrh, 4 parts of white peony, 4 parts of Impatiens, 4 parts of Panax notoginseng, 1 part of musk, 2 parts of dogwood, 4 parts of parasitic yellow, 8 parts of earthworm, 3 parts of Caulis Spatholobus, 2 parts of Dipsacus, 2 parts of notopterygium, 2 parts of licorice, 2 parts of pepper, and 3 parts of adhesive.

[0033] A method for preparing a traditional Chinese medicine microneedle transdermal drug patch of the present invention comprises the following steps:

[0034] (1) Weigh 4 parts of small bark bone, 4 parts of Moutan bark, 2 parts of Angelica sinensis, 5 parts of Zhicaowu, ...

Embodiment 2

[0041] A kind of traditional Chinese medicine microneedle transdermal drug delivery plaster according to the present invention, the raw material of plaster is according to weight: 6 parts of small bark bone, 6 parts of Moutan cortex, 10 parts of peony seed oil, 4 parts of Angelica sinensis, 8 parts of Aconitum aconitum 6 parts, Atractylodes 6 parts, Achyranthes bidentata 6 parts, Myrrh 8 parts, Paeoniae Alba 8 parts, Impatiens 8 parts, Panax notoginseng 8 parts, musk 3 parts, dogwood 4 parts, parasitic yellow 8 parts, earthworm 14 parts, 6 parts of Caulis Spatholobus, 5 parts of Dipsacus, 5 parts of notopterygium, 7 parts of licorice, 3 parts of pepper, and 6 parts of adhesive.

[0042] A method for preparing a traditional Chinese medicine microneedle transdermal drug patch of the present invention comprises the following steps:

[0043] (1) Weigh 6 parts of small bark bone, 6 parts of Moutan bark, 4 parts of Angelica sinensis, 8 parts of Zhicaowu, 6 parts of Atractylodes atra...

Embodiment 3

[0052] A kind of traditional Chinese medicine microneedle transdermal drug delivery patch according to the present invention, the raw materials of the plaster are: 4 parts of small bark bone, 5 parts of Moutan cortex, 7 parts of peony seed oil, 3 parts of Angelica sinensis, 6 parts of Aconitum aconiti 4 parts of atractylodes, 5 parts of Achyranthes bidentata, 6 parts of myrrh, 6 parts of white peony, 6 parts of Impatiens, 6 parts of Panax notoginseng, 2 parts of musk, 3 parts of dogwood, 6 parts of parasitic yellow, 10 parts of earthworm, 4 parts of Caulis Spatholobus, 4 parts of Dipsacus, 3 parts of notopterygium, 5 parts of licorice, 2 parts of pepper, and 4 parts of adhesive.

[0053] A method for preparing a traditional Chinese medicine microneedle transdermal drug patch of the present invention comprises the following steps:

[0054] (1) Weigh 4 parts of Xiaogu, 5 parts of Moutan Cortex, 3 parts of Angelica, 6 parts of Zhicaowu, 4 parts of Cangzhu, 5 parts of Achyranthes ...

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Abstract

The invention relates to a traditional Chinese medicine microneedle transdermal delivery patch and a preparation method thereof. The traditional Chinese medicine microneedle transdermal delivery patch adopts the following raw materials: common gendarussa herb, moutan cortex, peony seed oil, radix angelicae sinensis, prepared radix aconiti kusnezoffii, rhizoma atractylodis, radix achyranthis bidentatae, myrrha, paeoniae alba radix, impatiens balsamina, radix notoginseng, fructus corni, Balanophora involucrata Hook. F., pheretima, caulis spatholobi, radix dipsaci, rhizoma notopterygii, glycyrrhizae radix and Capsicum annuum L. fructus. The traditional Chinese medicine microneedle transdermal delivery patch is refined from pure Chinese herbal medicines according to a raw material ratio, is lasting in efficacy, only needs to be applied through external application, does not need to be orally taken, is safe and non-toxic, and does not have any side effect on human health, the peony seed oil can improve the permeability of medicines and reduce an allergy phenomenon caused by traditional ointments, a porous microneedle transdermal delivery mode is adopted, so that the traditional Chinese medicine microneedle transdermal delivery patch has a slow-release effect, in addition, the effective components of the medicines can directly act on the subcutaneous skin, the effect is good and quick, no injuries are caused to the skin, the pain of a patient can be obviously reduced, the traditional Chinese medicine microneedle transdermal delivery patchcan act on a focus for a long time through external application, and a treatment effect is obvious.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and relates to a traditional Chinese medicine microneedle transdermal drug patch and a preparation method thereof. Background technique [0002] Nowadays, with the increasing pressure of life, people are living in a fast-paced life. In addition, the usual diet is irregular and fast-food diet, resulting in people in a sub-health state, and long-term work increases the The risk of chronic diseases such as lumbar muscle strain and cervical spondylosis, and, with the deepening of aging, middle-aged and elderly people with waist, leg, neck, and shoulder pain account for more than 82% of the elderly population and continue to increase. For lumbar muscle strain, neck and shoulder pain and other chronic diseases, physical therapy includes massage, acupuncture, cupping, etc., which are only suitable for combined treatment, and although acupuncture treatment and electrotherapy have no toxic and side ef...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61M37/00A61P21/00A61P29/00A61K9/00A61K35/55A61K35/62
CPCA61K36/19A61K36/71A61K36/65A61K36/232A61K36/714A61K36/284A61K36/21A61K36/328A61K36/185A61K36/258A61K35/55A61K36/40A61K35/62A61K36/486A61K36/237A61K36/484A61K36/81A61K9/0021A61P29/00A61P21/00A61M37/0015A61K2236/15A61K2236/37A61M2037/0053A61K2300/00
Inventor 白晓东任志勇潘丽萍王继忠
Owner 河南佳普医药科技有限公司
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