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Composition for reducing uric acid and relieving gout and preparation method thereof

A technology for lowering uric acid and a composition is applied in the field of compositions for lowering uric acid and relieving gout and the preparation field thereof, which can solve the problems of liver and kidney side effects, cannot be taken for a long time, large side effects, etc., and achieves alleviation of gout symptoms, improvement of symptoms, The effect of lowering uric acid

Pending Publication Date: 2021-12-28
江苏协合转化医学研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a composition for lowering uric acid and relieving gout and its preparation method, so as to solve the existing drug intervention treatment proposed in the above-mentioned background technology, and the drugs for lowering uric acid have relatively large side effects after clinical trials: Excessive excretion of uric acid also excretes other trace elements from the body, which will cause hyponatremia, hypokalemia, and hypocalcemia. It cannot be taken for a long time, and it also has side effects on the liver and kidney.

Method used

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  • Composition for reducing uric acid and relieving gout and preparation method thereof
  • Composition for reducing uric acid and relieving gout and preparation method thereof
  • Composition for reducing uric acid and relieving gout and preparation method thereof

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Embodiment Construction

[0031] The present invention will be further described below in conjunction with the accompanying drawings.

[0032] A composition for lowering uric acid and relieving gout of the present invention, comprising a plain tablet and a coating;

[0033] The plain tablet comprises the following components and the parts by weight of each component: sorbitol: 10-200 parts; microcrystalline cellulose: 10-200 parts; xylitol: 50-100 parts; anserine: 50-300 parts Sour cherry powder: 10-300 parts; chitosan oligosaccharide: 40-250 parts; celery extract: 10-150 parts; -150 parts; Silicon dioxide: 4-24 parts; Magnesium stearate: 2-18 parts;

[0034] The coating includes the following components and the parts by weight of each component: hypromellose: 5-30 parts; titanium dioxide: 5-20 parts; coloring agent: 2-10 parts; polyethylene glycol 6000: 5-20 parts 25 parts; talcum powder: 5-20 parts.

[0035] The aforementioned composition for lowering uric acid and alleviating gout has 550-650 par...

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Abstract

The invention discloses a composition for reducing uric acid and relieving gout and a preparation method thereof. The composition has the effect of reducing uric acid, the uric acid can be effectively reduced after intervention for one month, the reduction amplitude is larger than 10%, the reduction amplitude of the uric acid reaches 37.55% after intervention for three months, the total effective rate is 88%, ingredients of the product are all food-grade, no adverse reaction exists in the eating process. When being combined with febuxostat for treatment, the traditional Chinese medicine composition can assist in reducing uric acid and relieving gout symptoms of patients, blood uric acid of the patients is reduced in a large range, gout nodules are obviously reduced, the traditional Chinese medicine composition has no harm to liver and kidney functions, the effect of reducing uric acid is not obvious in the initial stage of eating, but the symptoms of gout patients in 2 months, especially in the third month, are obviously improved. The uric acid level of a patient is obviously reduced, so that the pharmaceutical composition can also be used as an auxiliary product of a medicinal uric acid reducing product.

Description

technical field [0001] The invention relates to the technical field of preparation of a composition for reducing uric acid and alleviating gout, in particular to a composition for reducing uric acid and alleviating gout and a preparation method thereof. Background technique [0002] Hyperuricemia is a metabolic disease caused by the disorder of purine metabolism in the human body, resulting in increased uric acid in the blood. Urate crystals in patients with hyperuricemia are deposited in the synovium, synovial bursa, cartilage and other tissues, causing recurrent inflammatory diseases called gout. With the improvement of people's living standards and changes in diet structure, the incidence of hyperuricemia is increasing year by year. According to the data published in the "2017 White Paper on the Status of Gout in China", the number of patients with hyperuricemia in my country has reached 170 million, of which There are more than 80 million gout patients, and they are incr...

Claims

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Application Information

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IPC IPC(8): A61K38/05A61K9/36A61P19/06A61K36/87A61K31/722A61K31/375A61K31/426
CPCA61K38/05A61K36/736A61K31/722A61K36/23A61K36/287A61K36/87A61K31/375A61K31/426A61K9/2095A61K9/2054A61K9/2866A61K9/2893A61P19/06A61K2300/00
Inventor 程一林孙双鸽程晓紊陈顺亚王宇霞
Owner 江苏协合转化医学研究院有限公司