Stable pharmaceutical composition containing ethinylestradiol and norethindrone acetate
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 北京联嘉医药科技开发有限公司
- Publication Date
- 2022-03-04
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Abstract
Description
technical field
[0001] The invention relates to the field of pharmaceutical preparations. The invention provides a pharmaceutical composition for female contraception or treatment and prevention of climacteric syndrome with good stability. Background technique
[0002] Oral contraceptives usually contain a combination of synthetic progestin and estrogen. Both of these two hormone compounds can promote the maturation of female accessory sex organs and the emergence of secondary sexual characteristics, and maintain normal sexual desire and reproductive function. The compound preparation of estrogen ethinyl estradiol and progestin norethindrone acetate (optical rotation -32° to -38°) can be used for female contraception and treatment or prevention of menopausal syndrome.
[0003] Ethinyl estradiol is an orally bioavailable estrogen, which is used in almost all modern combined oral contraceptive formulations. The content in a single dose product is usually less than 100µg, and...