Adjustable constant-temperature experimental mouse acute stress model establishing device

Abstract

According to the technical scheme, the adjustable constant-temperature experimental mouse acute stress model building device is characterized in that the device comprises a water bath mechanism and a binding mechanism, the water bath mechanism comprises a water bath box and a base, and the base is provided with a lifting component, a display component, a heating component, a temperature measuring component and a control component; the binding mechanism comprises a mounting seat, a body binding assembly, a head binding assembly and a hip binding assembly; the bundle body assembly comprises two elastic wrapping pieces and a dismounting and mounting part, penetrating holes are formed in the elastic wrapping pieces, and through holes are densely distributed in the elastic wrapping pieces; the head binding assembly comprises a head binding frame, an upper sliding seat, an upper sliding rod and a head binding sleeve; limiting structures are arranged between the upper sliding seat and the head binding frame and between the upper sliding seat and the upper sliding rod; the hip binding assembly comprises a hip binding frame, a lower sliding seat, a lower sliding rod and a hip binding sleeve. Limiting structures are arranged between the lower sliding seat and the hip binding frame and between the lower sliding seat and the lower sliding rod. The head binding sleeve and the hip binding sleeve are both provided with cavities, and through holes are densely distributed in the head binding sleeve and the hip binding sleeve. And the binding effect on the laboratory mouse is effectively improved.

Description

technical field [0001] The invention relates to the technical field of instruments for medical experiments, and more specifically relates to an adjustable constant temperature experimental mouse acute stress model establishment device. Background technique [0002] In scientific research experiments, scientific research mice are the most widely used, most versatile and most strained experimental animals in the world. Because of its small size, docile temperament, strong reproductive ability, short reproductive cycle, and sensitivity to external stimuli, various toxins and pathogens; and the pituitary-adrenal system is well developed, if the research mice have a strong stress response to external stimuli, Hormone levels will rapidly undergo strong dynamic changes. Now it has become the model animal of choice for replicating animal models of human diseases and studying gene functions. Genetics and genetic disease research, reproduction research, immunology research and other...

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Problems solved by technology

[0003] However, in the existing experimental studies, the restraint of scientific research mice mostly adopts a tubular restraint device, such as a simple mouse cold restraint stress model manufacturing device disclosed by a Chinese patent with a notification number of CN203861377U. into the tubular restraint device, and then placed the restraint device in the water bath for experiments, but since the tubular restraint device cannot completely fit the volume of the research mouse, in order to facilitate the research mouse into the tubular restraint device, Usually, a slightly larger tubular restraint device is selected, so that the scientific research mouse can move and rotate in the tubular restraint device during the experiment, which can cause the research mouse to be injured by the stress response generated during the experiment, thereby changing the normal state of the mouse. Physiological indicators, affecting experimental results

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