Portable multifunctional visual microfluid equipment based on electric field regulation and control
A technology of electric field regulation and microfluidics, applied in fluid controllers, microscopes, laboratory containers, etc., can solve the problems of difficult handling of external equipment, complicated operation process, low integration, etc., to achieve enhanced controllability and multi- Task adaptability, good portability, and the effect of reducing the cost of use
Active Publication Date: 2022-03-22
HARBIN INST OF TECH
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Problems solved by technology
[0003] In order to solve the problems of the existing microfluidic electric operation equipment such as bulky volume, low integration, complicated operation process and difficult handling of required external equipment, the present invention provides a A Portable Multifunctional Visual Microfluidic Device Based on Electric Field Regulation
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[0058] Taking the function of using dielectrophoresis to achieve particle deflection as an example, the electric field regulation PCB1-2 can generate 16Vpp, 1MHz electrical signals through the circuit, and the original particles in the microfluidic chip such as Figure 7 As shown, the particles move from left to right, and it can be seen that there are particles in the two outlets on the right. Press the button switch 2-4 on the upper side to connect the circuit of the top cover component, and then apply an electric field signal to the chip, and the particles are deflected as Figure 8 shown. from Figure 8 It can be seen that the particles are deflected upward under the action of the electric field.
[0059] The device can quickly detect the influence of different voltage frequencies on the microfluidic chip, such as quickly observing the changes in particle size and the influence of voltage frequency changes on particle motion.
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The invention discloses portable multifunctional visual microfluid equipment based on electric field regulation and control, the microfluid equipment comprises a replaceable top cover assembly, an equipment shell assembly and a display transmission assembly, the replaceable top cover assembly is composed of a power transmission board, an electric field regulation and control PCB and a top cover; the shell assembly is composed of a shell, a power transmission probe, a detachable window plate and a button switch. The display transmission assembly is composed of a chip base, a copper column, a movable support, an adjustable microscope, a focusing bolt, an image transmission PCB, a battery and a micro-fluidic chip. The device is good in reliability, compact in structure, light in weight, good in portability and modularized, different top cover assemblies can be replaced according to different needs, electric field regulation and control can be conducted on microfluid, and the device can be applied to electric field regulation and control besides the basic functions of dielectrophoresis, induced charge electroosmosis, alternating-current electroosmosis, direct-current electric heating, alternating-current electric heating and the like. And the functions of agglomeration, sorting, deflection, microfluid mixing and the like of particles or cells can be realized.
Description
technical field [0001] The invention relates to a microfluidic operating device, in particular to a portable multifunctional visualized microfluidic device based on electric field regulation. Background technique [0002] Microfluidics is a multidisciplinary interdisciplinary technology involving mechanics, electronics, fluids, chemistry, materials, and biology. and manipulating objects. Using micro-nano-fabrication methods, microfluidic devices have realized the miniaturization and integration of large-scale, functionally dispersed traditional biochemical laboratories. Compared with biochemical research methods in traditional laboratories, microfluidic technology has significant advantages such as low cost, low reagent consumption, fast response speed and high analytical precision, so it is favored and concerned by researchers in many fields. However, the external experimental equipment of the current microfluidic device is complex and cannot work in a complex outdoor env...
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IPC IPC(8): B01L3/00G02B21/24G02B21/36
CPCB01L3/5027B01L3/502761B01L3/502753B01L3/50273G02B21/241G02B21/36B01L2300/06B01L2200/0647B01L2200/0668B01L2400/0424B01L2400/0418B01L2400/0442
Inventor 陶冶郭文尚任玉坤
Owner HARBIN INST OF TECH
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