Porcine epidemic diarrhea virus and application thereof

A technology for porcine epidemic diarrhea and diarrhea virus, applied in the field of biomedicine, can solve problems such as inability to produce protective effect, and achieve the effect of significant protective effect, strong immune effect, and reduction of infection rate and mortality rate.

Active Publication Date: 2022-04-15
GUANGZHOU GREAT BIOLOGICAL TECH
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, due to the prevalence of PEDV mutant strains, commercially available vaccines have been unable to produce effective protective effects, and the development of vaccines and related products that can effectively protect against PEDV mutant strains is of great significance to the aquaculture industry

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Porcine epidemic diarrhea virus and application thereof
  • Porcine epidemic diarrhea virus and application thereof
  • Porcine epidemic diarrhea virus and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0051] In order to make the object, technical solution and technical effect of the present invention clearer, the present invention will be further described in detail below in conjunction with specific embodiments. It should be understood that the specific implementations described in this specification are only for explaining the present invention, not for limiting the present invention.

[0052] The experimental materials and reagents used, unless otherwise specified, are conventional consumables and reagents that can be obtained from commercial channels.

[0053] Isolation and Identification of Porcine Epidemic Diarrhea Vaccine Strain CH-HuN

[0054] The porcine epidemic diarrhea virus CH-HuN strain in the examples of the present invention was isolated by the inventor in 2014 from the small intestine tissue of piglets from a pig farm in Chenzhou City, Hunan Province. The strain (classified and named: Porcine Infectious Diarrhea Virus, PEDV-HuN) was preserved in the Genera...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a porcine epidemic diarrhea virus and application thereof, the porcine epidemic diarrhea virus is named as PEDV-HuN, and is preserved in China General Microbiological Culture Collection Center on June 2, 2021, and the preservation number is CGMCC No.20280. The invention further discloses a preparation method of the porcine epidemic diarrhea virus. Compared with a traditional strain, the strain belongs to different branches and is stable in passage and high in virus titer. The inactivated vaccine prepared on the basis of the inactivated vaccine has a remarkable protection effect, can completely prevent invasion of current porcine epidemic diarrhea virus epidemic strains, reduces the infection rate and the death rate of the porcine epidemic diarrhea virus, reduces the breeding risk, and ensures the stability of the pig industry.

Description

technical field [0001] The invention belongs to the field of biomedicine, in particular to a porcine epidemic diarrhea virus and its application. Background technique [0002] Porcine epidemic diarrhea virus (PEDV) is an intestinal infectious disease that can cause pigs to have watery vomiting, diarrhea, and dehydration as the main characteristics, and the mortality rate is as high as 100%. In addition to causing direct economic losses to piglets, PEDV infection can also infect sows, resulting in reduced or stopped lactation, regurgitation, and estrus disorders, which are extremely harmful to the pig industry. [0003] Classical PEDV strains have weak infectivity and slow transmission speed, and are mainly characterized by endemic epidemics. However, in recent years, new PEDV variant epidemic strains have emerged continuously around the world, which are mainly characterized by fast transmission speed, high morbidity and high mortality. These PEDV mutant strains are differe...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C12N7/00A61K39/215A61P31/14C12R1/93
CPCY02A50/30
Inventor 魏平华
Owner GUANGZHOU GREAT BIOLOGICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap