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Preparation with high metagen content as well as preparation method and application thereof

An epigenetic and content technology, which is applied in the directions of medical preparations containing active ingredients, medical preparations with non-active ingredients, antidote, etc. Anti-Immune Aging Effects

Active Publication Date: 2022-04-26
广州市巴菲巴健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The preparations containing postbiotics currently on the market have a low content of postbiotics in the preparations, and there are very few postbiotic preparations with anti-immunoaging effects. The effect of postbiotic preparations is imminent

Method used

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  • Preparation with high metagen content as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1, a formulation with a high afterliferative content

[0039] The formulation with a high epigenetic content, comprising the following components and the number of parts of their mass:

[0040]60 parts of epigenetics, 0.5 parts of polyvinyl alcohol, 2 parts of absorption accelerator, 0.1 parts of stabilizer; the absorption accelerator is composed of sorbitol and L- fucose by mass ratio 4: 1; the stabilizer is composed of polyvinylpyrrolidone and hydroxypropyl cyclodextrin by mass ratio 2: 13.

[0041] The preparation method of the post-organism is:

[0042] (1) Take the fermentation material, add water, the amount of water added is 10 times the quality of the fermented material, stirring, the mixing speed is 600r / min, the mixing time is 20min, and the mixed material is obtained;

[0043] (2) to step (1) to add fermentation bacteria to the resulting mixed material, the fermentation bacteria by Lactobacillus casei, Lactobacillus planti and bifidobacterium longum infa...

Embodiment 2

[0049] Example 2, a formulation with a high afterliferative content

[0050] The formulation with a high epigenetic content, comprising the following components and the number of parts of their mass:

[0051] 70 parts of epigenetics, 1 part of polyvinyl alcohol, 5 parts of absorption accelerator, 0.3 parts of stabilizer; the absorption promoter is composed of sorbitol and L- fucose by mass ratio 6: 1; the stabilizer is composed of polyvinylpyrrolidone and hydroxypropyl cyclodextrin according to the mass ratio of 4: 10.

[0052] The preparation method of the post-organism is:

[0053] (1) Take the fermentation material, add water, the amount of water added is 20 times the quality of the fermented material, stirring, the mixing speed is 900r / min, the mixing time is 40min, and the mixed material is obtained;

[0054] (2) to step (1) to the resulting mixed materials added fermentation bacteria, the fermentation bacteria by Lactobacillus casei, Lactobacillus planti and Bifidobacterium ...

Embodiment 3

[0060] Example 3, a formulation with a high post-organism content

[0061] The formulation with a high epigenetic content, comprising the following components and the number of parts of their mass:

[0062] 64 parts of epigenetics, 0.7 parts of polyvinyl alcohol, 3 parts of absorption accelerator, 0.2 parts of stabilizer; the absorption accelerator is composed of sorbitol and L- fucose by mass ratio 5: 1; the stabilizer is composed of polyvinylpyrrolidone and hydroxypropyl cyclodextrin by mass ratio 3: 10.

[0063] The preparation method of the post-organism is:

[0064] (1) Take the fermentation material, add water, the amount of water added is 14 times the quality of the fermented material, stirring, the mixing speed is 800r / min, the mixing time is 25min, and the mixed material is obtained;

[0065] (2) to step (1) to add fermentation bacteria to the resulting mixed material, the fermentation bacteria by Lactobacillus casei, Lactobacillus planti and bifidobacterium longum infant...

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Abstract

The invention belongs to the technical field of biological agents, and particularly relates to a preparation with high metagen content and a preparation method and application thereof. The preparation with high metagen content provided by the invention is prepared from the following components in parts by mass: 60 to 70 parts of metagen, 0.5 to 1 part of polyvinyl alcohol, 2 to 5 parts of an absorption enhancer and 0.1 to 0.3 part of a stabilizer, the absorption enhancer is prepared from sorbitol and L-fucose; the stabilizing agent is prepared from polyvinylpyrrolidone and hydroxypropyl cyclodextrin. The preparation provided by the invention is high in metagen content and has an excellent immune aging resisting effect. In addition, the preparation method of the preparation with the high metagen content is simple, industrial implementation is easy, and large-scale application and popularization of the preparation are facilitated.

Description

Technical field [0001] The present invention belongs to the field of biologics technology, specifically relates to a formulation with a high progenetic content thereof and preparation methods and applications thereof. Background [0002] Epizootic refers to inactivated probiotic cells and their associated metabolic by-products, which have the ability to provide benefits to the health of the host, and have been widely accepted as: the probiotic is an inanimate microorganism and / or its components (including metabolites, cell components or cell-free mixtures) that are beneficial to the health of the host; including many different components, such as short-chain fatty acids, microbial cell components, extracellular polysaccharides, cell lysates, phosphine acids, peptidoglycans, active lipids, and organic acids. Compared to live probiotics, episophytes have a clear chemical structure, safe dosage parameters, and longer shelf life with good absorption, metabolism, distribution, and ex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61K47/26A61K47/32A61K47/40A61P39/06A61K35/745
CPCA61K35/747A61K35/745A61K47/32A61K47/26A61K47/40A61P39/06A61K2300/00
Inventor 孙梦洋王冠
Owner 广州市巴菲巴健康产业有限公司
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