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Preparation method of silica gel plaster

A silicone gel plaster, silicone gel technology, applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, sheet delivery, etc., can solve problems such as pain, excessive smell, and weak seasonal adhesion.

Pending Publication Date: 2022-05-06
德州昌诚新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention provides a preparation method of a silicone gel plaster to solve the problems of excessive pain when peeled off, heavy smell, weak seasonal paste and easy allergies in the prior art

Method used

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  • Preparation method of silica gel plaster
  • Preparation method of silica gel plaster
  • Preparation method of silica gel plaster

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1. Prepare traditional Chinese medicine microcapsule transdermal absorbent, concentrate the purified Chinese medicine at low temperature in vacuum to obtain concentrate A, fully stir the concentrate A: propylene glycol: azone according to the mass ratio of 100:0.1:0.02, and add gas phase II after stirring evenly Add the amount of silicon oxide until the viscosity of the main body is 2000-4000cp / 25 degrees, then add polyvinyl alcohol aqueous solution at a ratio of 10% and stir, stir evenly, and then dry to remove excess water for later use.

[0018] 2. To prepare the sticky body, add 15g of the traditional Chinese medicine microcapsule transdermal agent into 50g of polydimethylsilane three times and stir well. After stirring evenly, put it into a vacuum tank and heat it up to 60 degrees and continue stirring for about 6 hours to remove excess water. After cooling, put it at room temperature Add 0.5g of propylene glycol, 0.2g of menthol, 0.05g of antioxidant, 0.2g of azone...

Embodiment 2

[0021] 1. Prepare traditional Chinese medicine microcapsule transdermal absorbent, concentrate the purified Chinese medicine at low temperature in vacuum to obtain concentrate A, fully stir the concentrate A: propylene glycol: azone according to the mass ratio of 100:0.1:0.02, and add gas phase II after stirring evenly Add the amount of silicon oxide until the viscosity of the main body is 2000-4000cp / 25 degrees, then add polyvinyl alcohol aqueous solution at a ratio of 10% and stir, stir evenly, and then dry to remove excess water for later use.

[0022] 2. To prepare the sticky body, add 15g of the traditional Chinese medicine microcapsule transdermal agent into 45g of polydimethylsilane three times and stir thoroughly. After stirring evenly, put it in a vacuum tank and heat it up to 60 degrees and continue stirring for about 6 hours to remove excess water. After cooling, put it at room temperature Add 0.4g of propylene glycol, 0.15g of menthol, 0.05g of antioxidant, 0.15g of...

Embodiment 3

[0025] 1. Prepare traditional Chinese medicine microcapsule transdermal absorbent, concentrate the purified Chinese medicine at low temperature in vacuum to obtain concentrate A, fully stir the concentrate A: propylene glycol: azone according to the mass ratio of 100:0.1:0.02, and add gas phase II after stirring evenly Add the amount of silicon oxide until the viscosity of the main body is 2000-4000cp / 25 degrees, then add polyvinyl alcohol aqueous solution at a ratio of 10% and stir, stir evenly, and then dry to remove excess water for later use.

[0026] 2. To prepare the sticky body, add 15g of the traditional Chinese medicine microcapsule transdermal agent into 42g of polydimethylsilane three times and stir thoroughly. After stirring evenly, put it in a vacuum tank and heat it up to 60 degrees and continue stirring for about 6 hours to remove excess water. After cooling, put it at room temperature. Add 0.4g of propylene glycol, 0.15g of menthol, 0.05g of antioxidant, 0.15g o...

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Abstract

According to the preparation method of the silica gel plaster, the silica gel plaster is composed of a base material layer, an adhesive layer and a traditional Chinese medicine microcapsule transdermal absorbent, the base material layer is a backing layer, and the adhesive layer is prepared from polymerized silica gel formed by polydimethylsilane, vinyl polysiloxane and cellulose and the traditional Chinese medicine microcapsule transdermal absorbent. The traditional Chinese medicine microcapsule transdermal absorbent is composed of a traditional Chinese medicine extract, propylene glycol, menthol, azone and fumed silica. The unique superiority of the silica gel is fully utilized, the silica gel is fused into a traditional plaster patch through technical improvement, the problem that the silica gel and alcohol substances are insoluble is well solved through a saturated cellulose technology, and the silica gel plaster patch is free of irritation, low in allergy rate, good in skin affinity and free of toxic and side effects. When the plaster patch is stripped from the skin, pain and pain caused by taking down body hair together are avoided, the silica gel has a good moist feeling on the surface of the skin, body surface moisture can be prevented from being evaporated, cuticles can be better softened, medicine can be better absorbed, and the treatment effect of the medicine can be achieved through a tendon channel.

Description

technical field [0001] The invention relates to the technical field of production and processing of medical products, in particular to a method for preparing a silicone gel plaster. Background technique [0002] Plaster plaster, commonly known as dog skin plaster, began to be used in the Qing Dynasty to promote blood circulation and remove stasis, nourish qi and nourish blood, dredge meridians and collaterals, strengthen tendons and bones, relax tendons and collaterals, resuscitate bones, dispel wind and cold, and other symptoms. Plaster plaster is an important part of Chinese medicine, and it is a unique Chinese medicine external therapy in Chinese medicine. It has a history of two thousand years and is widely used in the treatment of various diseases. It is welcomed by the masses. It is the use of drugs to treat diseases It is a kind of therapy that exerts drug therapeutic effect on the body surface or the affected part through the pathway of drug absorption and tendons. T...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/34A61K47/38
CPCA61K9/7069A61K9/7046A61K47/34A61K47/38
Inventor 马跃华荣首文周永发李翔李绪海
Owner 德州昌诚新材料有限公司
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