Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Fruit polyphenol and probiotic composition as well as preparation method and application thereof

A technology of probiotics and compositions, applied in the direction of bacteria used in food preparation, drug combinations, separation/purification of carbonyl compounds, etc., can solve problems such as disorders, death, obstacles, etc.

Pending Publication Date: 2022-06-07
上海朗泰凯尔生物技术有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of chemical weight-loss drugs can lead to a series of adverse reactions such as liver and kidney damage, cardiovascular dysfunction, electrolyte imbalance, and even death.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fruit polyphenol and probiotic composition as well as preparation method and application thereof
  • Fruit polyphenol and probiotic composition as well as preparation method and application thereof
  • Fruit polyphenol and probiotic composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A fruit polyphenol and probiotic composition of the present embodiment includes: fruit polyphenol and probiotic bacteria, and the fruit polyphenol includes blueberry polyphenol, blueberry polyphenol derivative-1, prune polyphenol, and prune polyphenol derivative Compound-1, the structural formula of blueberry polyphenol derivative-1 is The structural formula of prune polyphenol derivative-1 is Probiotics include Lactobacillus plantarum, Lactobacillus acidophilus, and Lactobacillus casei. Calculated by mass percentage, the mass percentage of the fruit polyphenols and probiotics is 2.1:0.15.

[0038] The preparation method of this embodiment includes:

[0039] 1) Preparation of blueberry polyphenols

[0040] Weigh the fresh blueberry fruit with no damage to the skin, add 80% pre-cooled ice acetone solution, crush 5min×10000g in a high-speed homogenizer masher, and perform crushing treatment. Suction filtration to collect the supernatant. The pomace in the lower lay...

Embodiment 2

[0089] The difference between this example and Example 1 is that a fruit polyphenol and probiotic composition in this example includes: fruit polyphenols and probiotics, and the fruit polyphenols include blueberry polyphenols and blueberry polyphenol derivatives -1, the pre-cooled ice acetone solution selected for the preparation of blueberry polyphenols is 40% acetone, and probiotics include Lactobacillus plantarum, Lactobacillus acidophilus, and calculated by mass percent, the mass percents of described fruit polyphenols and probiotics are 1.1:0.02.

[0090] The preparation method of the composition of this example: the difference from Example 1 is that blueberry polyphenols and blueberry polyphenol derivatives-1 are prepared only from fresh blueberry fruits. The specific formula is as follows: blueberry polyphenol 1 g, blueberry polyphenol derivative-1 Material-1 0.1g, Lactobacillus plantarum 0.01g, Lactobacillus acidophilus 0.01g.

[0091] Mix the blueberry polyphenols an...

Embodiment 3

[0094] The difference between this embodiment and Embodiment 1 is that the composition of fruit polyphenols and probiotics in this embodiment includes: fruit polyphenols and probiotics, and the fruit polyphenols include prune polyphenol and prune polyphenol. Derivative-1, the pre-cooled ice acetone solution selected for the preparation of prune polyphenols is 20% acetone, and the probiotics include Lactobacillus casei, and calculated by mass percentage, the mass percentages of the fruit polyphenols and probiotics are 112- 2020:3.

[0095] The preparation method of the composition of this example: the difference from Example 1 is that prune polyphenol and prune polyphenol derivative-1 are prepared only from fresh prune fruit, and the specific formula is as follows: prune polyphenol 10 g, Prune polyphenol derivative-1 0.01g, Lactobacillus casei 0.1g.

[0096] Mix the prune polyphenol and prune polyphenol derivative-1 of the above proportions in proportion, and freeze-dry to obt...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of medicine preparation, and particularly relates to a fruit polyphenol and probiotic composition as well as a preparation method and application thereof. The invention relates to a fruit polyphenol probiotic beverage, which comprises fruit polyphenol and probiotics, and the mass percentage of the fruit polyphenol to the probiotics is (20.2-11200): 3 according to the mass percentage of the fruit polyphenol to the probiotics. According to the invention, a simple separation process of fruit polyphenol and probiotic functional active components with functions of reducing blood sugar, reducing blood fat and losing weight is optimized based on a high-fat and high-sugar diet obesity model mouse. The fruit polyphenol component and the probiotics with the functions of reducing blood sugar, reducing blood fat and losing weight are optimally combined, so that the composition has very remarkable activity when being used for reducing blood sugar, reducing blood fat and losing weight, and has no side effect.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparation, and particularly relates to a fruit polyphenol and probiotic composition and a preparation method and application thereof. Background technique [0002] Obesity refers to a certain degree of excess weight or a thick layer of fat, and a state of accumulation of triglycerides in the body. There are many and complex causes of obesity, which are often related to diet, environment, certain drugs, living habits and mental factors. Among them, high-fat diet is an important factor that induces obesity. Obesity will affect major systems. For example, the accumulation of fat in the abdomen or diaphragm will reduce lung capacity, resulting in decreased pulmonary ventilation; obesity may lead to increased prevalence of cardiovascular diseases such as hypertension; secondly, obesity will induce a series of psychological problems. [0003] At present, the weight loss drugs for obesity mai...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61K31/11A61P3/10A61P3/06A61P3/04C07C45/78C07C49/84A23L33/105A23L33/135
CPCA61K35/747A61K31/11A61P3/10A61P3/06A61P3/04C07C45/78A23L33/105A23L33/135A23V2002/00A23V2400/125A23V2400/113A23V2400/169A61K2300/00C07C49/84A23V2200/328A23V2200/3262A23V2200/332A23V2250/2132Y02A40/90
Inventor 刘杰宗睿王文雅郑曼陈能花栗伟王怀玲刘晓蕾
Owner 上海朗泰凯尔生物技术有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com