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Preparation method of kava compound extract, compound extract and application

A compound extract and extract technology are used in skin care preparations, medical preparations containing active ingredients, drug combinations, etc., which can solve the problems of easy oxidative inactivation of ingredients, formation of irritants, and content reduction, and achieve anti-inflammatory effects. Better pain relief, enhanced stability, reduced content reduction

Pending Publication Date: 2022-07-22
广州伽能生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the above ingredients are prone to oxidative inactivation, discoloration, and formation of irritants
The traditional kava preparation process has high temperature or sterilization process, which is easy to oxidize, causing discoloration, lower content, and the produced oxidation products become new stimuli. Therefore, there is still room for improvement

Method used

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  • Preparation method of kava compound extract, compound extract and application
  • Preparation method of kava compound extract, compound extract and application
  • Preparation method of kava compound extract, compound extract and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] A preparation method of kava composite extract, comprising the following steps:

[0054] Step 1), prepare the extract of thorn prickly pear cactus leaf, which specifically includes:

[0055]Step 1-1), mix 150 g of thorn cactus leaf slices with water, and extract by external circulation at 90° C. for 2 hours to obtain an extract, and the quality of the water is 10 times that of the thorn cactus leaf.

[0056] Step 1-2), adding chitosan to the extract for flocculation, stirring at room temperature for 0.5h, standing for 2h, centrifuging until clarification, taking the centrifuge, the input quality of chitosan is 0.05% of the quality of the extract.

[0057] Step 1-3), the centrifuged liquid is concentrated to a crude drug ratio of 1 g / ml, that is, 150 ml of concentrated liquid is obtained.

[0058] Step 1-4), the concentrated solution is adsorbed through a D101 macroporous resin column, and then eluted through 3 times the column volume of ethanol with a concentration of ...

Embodiment 2

[0070] A preparation method of kava composite extract, comprising the following steps:

[0071] Step 1), prepare the extract of thorn thorn cactus leaf, which specifically includes:

[0072] Step 1-1), mix 150 g of thorn cactus leaf slices with water, and extract with external circulation at 85° C. for 2.5 hours to obtain an extract, and the quality of the water is 12 times that of the thorn cactus leaf.

[0073] Step 1-2), add chitosan to the extract for flocculation, stir at room temperature for 1h, stand for 2.5h, centrifuge until clarification, take the centrifuge, and the input quality of chitosan is 0.05% of the quality of the extract.

[0074] Step 1-3), the centrifuged liquid is concentrated to the crude drug ratio of 1.5g / ml, that is, 100ml of concentrated liquid is obtained.

[0075] Step 1-4), the concentrated solution is adsorbed through a D101 macroporous resin column, and then eluted through 4 times the column volume of ethanol with a concentration of 50% to obt...

Embodiment 3

[0087] A preparation method of kava composite extract, comprising the following steps:

[0088] Step 1), prepare the extract of thorn thorn cactus leaf, which specifically includes:

[0089] Step 1-1), mix 180 g of thorn cactus leaf slices with water, and extract with external circulation at 88° C. for 2 hours to obtain an extract, and the quality of the water is 11 times that of the thorn cactus leaf.

[0090] Step 1-2), adding chitosan to the extract for flocculation, stirring at room temperature for 0.5h, standing for 2h, centrifuging until clarification, taking the centrifuge, the input quality of chitosan is 0.05% of the quality of the extract.

[0091] In step 1-3), the centrifuged liquid was concentrated to a crude drug ratio of 1.2 g / ml, that is, 150 ml of concentrated liquid was obtained.

[0092] Step 1-4), the concentrated solution is adsorbed through a D101 macroporous resin column, and then eluted through 3.5 times the column volume of 50% ethanol to obtain an el...

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Abstract

The invention relates to the field of plant extracts, and particularly discloses a preparation method of a kava composite extract, the composite extract and application, the preparation method of the kava composite extract comprises the following steps: 1) preparing an opuntia streptacantha leaf extract; the preparation method comprises the following steps of 1, preparing a kava root extract, 2, carrying out hyperimbibition-freezing-microwave synergistic cell wall crushing to prepare a kava root extract, and 3, adding a cactus streptacantha leaf extract into the kava root extract, and carrying out stirring to obtain the kava composite extract.The preparation method has the advantage that kava lactone oxidation is reduced.

Description

technical field [0001] The invention relates to the field of plant extracts, in particular to a kava composite extract and a preparation method and application. Background technique [0002] The roots, stems and fresh leaves of kava have good medicinal value and have anti-inflammatory, antibacterial, insecticidal, antispasmodic, local anesthetic and other effects, and can also treat convulsions, asthma, anxiety, depression, and promote Sleep and improve sleep quality also have significant curative effects, and the toxic and side effects are small. [0003] In the field of daily chemicals, kava extract is mainly used as a plant extract active for soothing nerve conduction. It can make neurons hyperpolarize or depolarize by non-specific regulation of GABA receptors, which can quickly relieve various skin discomforts. It also has a better soothing and anti-inflammatory effect. [0004] The main functional components of kava are unsaturated lactones, such as buckwheat, methyle...

Claims

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Application Information

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IPC IPC(8): A61K36/67A61K8/9789A61P29/00A61Q19/00
CPCA61K36/67A61K36/33A61K8/9789A61P29/00A61Q19/00A61K2236/15A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2236/55A61K2800/10A61K2300/00
Inventor 陈贤
Owner 广州伽能生物科技有限公司
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