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Application of diethyl ether in resisting coronavirus infection

A coronavirus and ether technology, applied in the application field of ether in anti-coronavirus infection drugs, can solve problems such as body poisoning, body intolerance, and the inability of virus infection sites to reach effective concentrations, etc.

Pending Publication Date: 2022-08-02
邱瑞宝
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, there is currently no effective anti-coronavirus drug that inhibits the proliferation of coronavirus in the body, and the body cannot tolerate heat inactivation above 56°C
The direct use of the coronavirus inactivator cannot reach an effective concentration at the site of the virus infection, and a large amount of use will cause the body to be poisoned

Method used

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  • Application of diethyl ether in resisting coronavirus infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Preparation of ether emulsion. Add 10 g of emulsifier phospholipid to 30 g of ether, and stir to dissolve. The fully dissolved ether phospholipid solution is added to 1000 g of water, and stirred at high speed until the emulsification is complete to obtain ether emulsion.

Embodiment 2

[0025] Detection of the effect of ether against coronavirus infection

[0026] Chicks were infected with live vaccine of chicken infectious bronchitis virus H52 strain in coronavirus, and the anti-coronavirus effect of ether preparation was investigated.

[0027] Take 100 7-day-old chicks and divide them into 5 experimental groups with 20 chicks in each group. Group A: the blank control group was not inoculated with the virus and no drug was given; Group B: the drug control group was only given the drug but not inoculated with the virus; group D: the administration group started on the day of virus inoculation (inoculation with live chicken infectious bronchitis vaccine H52 strain); group E: the administration group started on the 2nd day after inoculation with virus (inoculated with chicken infectious bronchitis live vaccine H52 strain) .

[0028] The live chicken infectious bronchitis vaccine (strain H52) was diluted with normal saline and inoculated intranasally, 1 drop f...

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Abstract

The invention discloses an application of diethyl ether in preparation of an anti-coronavirus drug. Targeted dosage forms of diethyl ether are provided. The diethyl ether preparation has a remarkable effect in an anti-coronavirus infection test.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of ether in an anti-coronavirus infection drug. Background technique [0002] Coronaviruses are enveloped RNA viruses that belong to the genus Coronavirus in the family Coronaviridae. Can cause respiratory, gastrointestinal and nervous system infections in humans and animals. [0003] The coronavirus was first isolated from chickens in 1937. The diameter of the virus particle is 60-200nm, with an average diameter of 100nm. It is spherical or elliptical and has polymorphism. The virus has an envelope, and there are spines on the envelope. The whole virus is like the corona, and the spines of different coronaviruses are obviously different. Tubular inclusion bodies can sometimes be seen in coronavirus-infected cells. [0004] Human diseases caused by coronavirus are mainly respiratory system infections. Coronavirus is one of the main pathogens of ...

Claims

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Application Information

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IPC IPC(8): A61K31/08A61P31/14
CPCA61K31/08A61P31/14
Inventor 邱瑞宝
Owner 邱瑞宝
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