Soluble anti-inflammation, antibiotic and hemostatic gauze and method for making the same

Abstract

The invention provides a soluble anti-inflammatory, antibacterial and hemostatic gauze and a processing method thereof. The gauze uses amino acids to condense sulfonamide drugs on soluble fibers. The processing method of soluble anti-inflammatory, antibacterial and hemostatic gauze comprises the following sequential steps: (1) soaking the degreased gauze in a chloroacetic acid solution at normal temperature; (2) reacting the gauze processed in step (1) with amino acid; Step (2) soaking the treated gauze in NaOH saturated solution for etherification reaction; (4) adding hydrochloric acid to the treated gauze in step (3) in ethanol aqueous solution to adjust the pH to 5.4-7.6; (5) washing the gauze No residue on the surface; (6) the sulfonamides are reacted with the gauze treated in step (5). The gauze does not cause secondary trauma to the wound, the drug is released evenly and continuously, the drug effect lasts for a long time, and can provide nutrients for the wound, so that the wound heals quickly.

Description

Technical field [0001] The invention relates to a gauze for external application on wounds, in particular to a soluble anti-inflammatory, antibacterial and hemostatic gauze, and further relates to a processing method of the above-mentioned soluble anti-inflammatory, antibacterial and hemostatic gauze. Background technique [0002] Since the discovery of sulfonamides in 1935, they are the earliest synthetic chemotherapy drugs that are effective in the treatment of systemic infections. After the 1940s, the development of antibiotics and the emergence of synthetic quinolones in the 1970s partially replaced sulfa drugs. But because it still has unique advantages, it has good curative effect on certain infectious diseases (such as meningitis, plague), easy to use, stable properties, and low price. After combined use, most of them enhance their antibacterial efficacy and antibacterial range, and sulfonamides still have a certain status in clinical treatment. At present, there ar...

AI Technical Summary

Problems solved by technology

[0003] The present invention overcomes the shortcomings of the existing sulfonamide topical ointment or powder medicines in the treatment of external wounds, the dosage is limited, the smearing or external application is inconvenient, and the wound is easy to bind with gauze after the wound scabs, causing secondary trauma of the wound. A kind of soluble anti-inflammatory, antibacterial and hemostatic gauze, the gauze will not cause secondary trauma to the wound, the drug is released evenly and continuously, the drug effect lasts for a long time, and can provide nutrients for the wound, and the wound heals quickly