Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Conversion process of primary alcohol, hexamethylene glycol, tertiary amyl alcohol or cyclohexanol into halohydrocarbon in acid ionic liquid [Hmim] X,X==Cl,Br or I)

A technology of acidic ionic liquid and hexanediol, which is applied in the preparation of halogenated hydrocarbons, chemical instruments and methods, organic chemistry, etc., can solve the problems of unstable yield and long reaction time, and achieve the effect of environmental friendliness and simple process

Inactive Publication Date: 2005-11-02
EAST CHINA NORMAL UNIV
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in this document, still need to use inorganic or organic acid as catalyst, and reaction time is long, and yield is also unstable

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Conversion process of primary alcohol, hexamethylene glycol, tertiary amyl alcohol or cyclohexanol into halohydrocarbon in acid ionic liquid [Hmim] X,X==Cl,Br or I)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 100g Brφnsted acidic ionic liquid [Hmim] + Cl - Put 8.1g of n-butanol into the reaction flask, stir, heat, control the temperature at 110°C, react for 12 hours, let the reaction solution stand, settle by gravity, and separate the layers to obtain 96% yield of n-butane chloride. Add 10.8g of 37% hydrochloric acid solution to the Brφnsted acidic ionic liquid in the lower layer, and the regenerated ionic liquid can be recycled after evaporating water.

Embodiment 2

[0015] 100g Brφnsted acidic ionic liquid [Hmim] + Br - and 8.1 g of n-butanol were placed in a reaction flask, stirred, heated, and the temperature was controlled at 110° C. to react for 12 hours. The reaction solution was left to stand, gravity settled, and layered to obtain n-butane bromide with a yield of 98%. Add 18.9g of 47% hydrobromic acid solution to the Brφnsted acidic ionic liquid in the lower layer, and the regenerated ionic liquid can be recycled after distilling off the water.

Embodiment 3

[0017] 100g Brφnsted acidic ionic liquid [Hmim] + I - Put 8.1g of n-butanol into the reaction flask, nitrogen protection, stirring, heating, control the temperature at 60°C, react for 20 hours, let the reaction solution stand, settle by gravity, separate layers to obtain n-octane iodide, yield 99% . Add 29.8g of 47% hydroiodic acid solution to the Brφnsted acidic ionic liquid in the lower layer, and the regenerated ionic liquid can be recycled after evaporating water.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to the conversion process of primary alcohol or cyclohexanol in methyl imidazole salt halide and belongs to the field of organic chemical reaction method. The ionic liquid is made to mix with primary alcohol or cyclohexanol through stirring, and the mixture is heated, let stand, gravitationally deposited and separated to obtain halohydrocarbon with the yield being 85-100%. In the reaction, the ionic liquid is used also as catalyst, halogenation reagent and solvent. The present invention has the advantages of high yield, simple technological process, circular use of catalyst and solvent, being environment friendly, etc.

Description

technical field [0001] The present invention relates to acidic ionic liquids [Hmim] + x - , X=Cl, Br, I, i.e. the method for converting primary alcohol, hexanediol, tert-amyl alcohol or cyclohexanol into halogenated hydrocarbons in halomethylimidazolium salts, to be precise, involves Brφnsted acidic ionic liquid [Hmim] + x - , X=Cl, Br, I, that is, the method for converting primary alcohol, hexanediol, tert-amyl alcohol or cyclohexanol in halogenated methylimidazolium salts into halogenated hydrocarbons, which belongs to the technical field of new methods of organic chemical reactions. Background technique [0002] Halides are important intermediates in the pharmaceutical industry. The halogenation method of the background art is usually carried out by carrying out an alcohol and an inorganic salt containing a halide ion under the catalysis of a large amount of concentrated sulfuric acid. The residual waste acid after the reaction causes environmental...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07C17/00C07C19/00
Inventor 汤杰孙靖郑瑞吴海虹杨帆何鸣元
Owner EAST CHINA NORMAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com