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Medicine composition

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, skin diseases, etc., to achieve obvious excretion effect, eliminate skin roughness and pimples

Inactive Publication Date: 2006-08-09
SS PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, the medicaments for treating constipation in the past cannot fully meet the needs, and it is necessary to develop medicaments with better effects in treating constipation.

Method used

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  • Medicine composition
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0028] List experimental examples and test examples below to describe the present invention in detail, but the present invention is not limited to these

[0029] Examples etc.

Embodiment 1

[0082] (a) Fabrication of center tablet

[0083] The center tablet (original tablet) composed of Table 3 below was used to make 55 mg tablets each with a pestle of 5.5 mmφ and 4.5 R. The hardness of this tablet was 2.8 kgf, and the disintegration time (test liquid; water) was 6 to 8 minutes.

[0084] Element

1 tablet (mg)

Bisacodyl

5.0

Calcium Sennoside

13.3

Vitamin B 6 (Vitamin B hydrochloride 6 )

5.0

Vitamin B 2 (riboflavin)

2.0

Microcrystalline Cellulose PH-101

5.5

lactose

22.7

Talc

0.5

Magnesium stearate

1.0

total

55.0

[0085] 4.7 kg of the tablet was loaded into a ventilated flat bottom coating machine (Hicoater HCT-48; manufactured by Freund Industry Co., Ltd.), at a supply air temperature of 50° C., an article temperature of 45° C., and a rotation speed of 16 revolutions per minute (rpm) Under conditions, the plasticizer solu...

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Abstract

This medicament is a medicinal composition containing bisacodyl, sennoside or its salt and vitamins as effective components, and is used as an aperient for treating constipation.

Description

technical field [0001] The present invention relates to a pharmaceutical composition, especially a pharmaceutical composition that has therapeutic effects on promoting defecation and on skin roughness and pimples related to constipation. Background technique [0002] Constipation refers to symptoms of less frequent bowel movements and fewer bowel movements than when healthy, resulting in discomfort. Drugs for treating constipation include two types of drugs, "laxatives" that act on the small intestine and "laxatives" that act on the large intestine, but generally "laxatives" are mainly used as drugs for treating constipation. [0003] In addition, laxatives include: "saline laxatives", which supply water to the intestines by increasing the osmotic pressure in the intestines; Give stimulation to the intestinal wall, etc. General pharmaceutical products mainly use stimulant laxatives that stimulate the large intestine. [0004] However, the laxatives provided conventionally...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61K9/16A61K9/14A61P1/10A61K31/4402A61K31/4415A61K31/525A61P17/08
CPCA61K31/4402A61K31/4415A61K31/525A61K31/704A61K2300/00
Inventor 幸田伸子末广义兴坂井裕贵神户英芳小贯洋一
Owner SS PHARMA CO LTD