Method for preparing powdered injection of 'Shuanghuanglian' formulation

Abstract

The invention discloses a preparation method of Shuanghuanglian powder injection for injection, which relates to a preparation method of traditional Chinese medicine freeze-dried injection. The existing freeze-drying method has the defects that the drug quality is not easy to control and the yield is not high, and the prepared drug has poor clinical curative effect and many adverse reactions. According to the preparation method of the present invention, the ratio of 1 part of honeysuckle, 2 parts of forsythia and 1 part of scutellaria baicalensis is used to prepare materials, and then the three kinds of raw materials are respectively extracted and then mixed for preparation to obtain Shuanghuanglian powder injection for injection. The Shuanghuanglian powder injection prepared by the freeze-drying method of the present invention is dried at a low temperature, so the active ingredients of the medicine are not easy to be destroyed, the clinical curative effect is good, and the medicine particles maintain the original state and are easy to dissolve; the injection produced by the method of the present invention Shuanghuanglian powder injection has good clinical curative effect and few adverse reactions, which is conducive to popularization and application.

Description

Technical field: [0001] The invention relates to a preparation method of a traditional Chinese medicine freeze-dried injection. Background technique: [0002] Shuanghuanglian for injection has aqueous injections and powder injections. The aqueous injections have the disadvantages of poor stability, easy damage during transportation, and turbidity and precipitation during long-term storage; the preparation of powder injections includes spray-drying methods and freeze-drying methods. Spraying down, so the active ingredients of the drug are easily destroyed, and the chance of drug contamination is increased, and the drug particles are easy to accumulate, resulting in difficulty in dissolving, thereby affecting the efficacy of the drug; the existing freeze-drying method is difficult to control the quality of the drug The disadvantage is not high, and the prepared medicine has bad clinical curative effect and many adverse reactions. Invention content: [0003] The purpose of t...

AI Technical Summary

Problems solved by technology

[0002] Shuanghuanglian for injection has aqueous injections and powder injections. The aqueous injections have the disadvantages of poor stability, easy damage during transportation, and turbidity and precipitation during long-term storage; the preparation of powder injections includes spray-drying methods and freeze-drying methods. Spraying down, so the active ingredients of the drug are easily destroyed, and the chance of drug contamination is increased, and the drug particles are easy to accumulate, resulting in difficulty in dissolving, thereby affecting the efficacy of the drug; the existing freeze-drying method is difficult to control the quality of the drug The defect is not high, and the clinical efficacy of the prepared medicine is not good, and there are many adverse reactions