Unlock instant, AI-driven research and patent intelligence for your innovation.

Puerarin extracting method

An extraction method and technology of puerarin, applied in the field of extraction and preparation of traditional Chinese medicine, can solve the problems of unfavorable environmental protection, poor effect, low puerarin content, etc., and achieve the effect of being beneficial to environmental protection and short process flow

Inactive Publication Date: 2007-02-14
安康汉阴华晔植物药业有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Puerarin is extracted from kudzu root Chinese medicinal materials. The commonly used extraction methods are water extraction and alcohol extraction, and then polyamide column chromatography. Therefore, the extraction time is long, the effect is poor, and the yield is low. Some people have developed a method that does not use polyamide The method of column chromatography is to improve yield and reduce cost. For example, the publication number is CN1276378A, and the name is "A new method for extracting high-purity medicinal puerarin", which proposes a method for extracting high-purity medicinal puerarin from Pueraria mirifica with water instead of alcohol. The new method of using puerarin, the process is to extract puerarin with water and then separate the extract, concentrate the extract into a paste and then dry it into powder, dissolve the dry powder in a solvent, filter and crystallize to obtain puerarin
The disadvantage of this method is that water extraction produces a large amount of waste liquid, which is not conducive to environmental protection, and the yield is low, and the puerarin content is also low

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Take 1,000 grams of dried kudzu root, put it into a container, add 8,000 ml of n-butanol into the container, heat to 50°C and soak for 6 hours, separate the n-butanol extract, and add n-butanol twice to the container, each time Add 5000 milliliters of n-butanol, soak for 3 hours, and separate the n-butanol extract. Combine 3 times of n-butanol extracts and concentrate to a paste, add 200 ml of glacial acetic acid crystals to the paste, filter, and further recrystallize with water to obtain 10.1 grams of finished puerarin with a puerarin content of 99.21%.

Embodiment 2

[0012] Take 1,000 grams of dried kudzu root, put it into a circular extractor, add 9,000 milliliters of n-butanol, and extract it circularly for 6 hours, then evaporate and recover n-butanol to obtain a paste, add 200 milliliters of glacial acetic acid crystals to the paste, filter, and water Recrystallize to obtain 12.1 grams of finished puerarin, and the puerarin content is 99.20%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

This invention belongs to Chinese medicine abstracting making technology, concretely relates to a pueraria extracting method, abstracts a short technique flow without residue exhaustion and high pueraria contents. This method uses the root of kudzu vine as the raw material and the normal butyl alcohol as solution to abstract, the condensing abstract agent recycles normal butyl alcohol to get cream that crystallizes the pueraria. This invention has short technique flow, the pue raria content of finished products is above 99% and is good for fully utilization of resources. Normal butyl alcohol can be reused after being recycled, and the producing procedure is without residue and is good for environmental protection.

Description

technical field [0001] The invention belongs to the technical field of extraction and preparation of traditional Chinese medicines, and in particular relates to a method for extracting puerarin. Background technique [0002] Pujisu is a vasodilator drug that can expand coronary arteries and cerebral blood vessels, reduce myocardial oxygen consumption, improve blood circulation and anti-platelet aggregation, and is suitable for the treatment of coronary heart disease, angina pectoris, myocardial infarction, retinal arteriovenous occlusion , Sudden deafness and other diseases, so there is a large demand in the pharmaceutical market. Puerarin is extracted from kudzu root Chinese medicinal materials. The commonly used extraction methods are water extraction and alcohol extraction, and then polyamide column chromatography. Therefore, the extraction time is long, the effect is poor, and the yield is low. Some people have developed a method that does not use polyamide The method o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07H17/07C07H1/08
Inventor 胡子朗南怀炼陈贵伟
Owner 安康汉阴华晔植物药业有限公司