Hairy holly root drip pill and its preparation method
A technology of holly and dripping pills, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problem of first-pass bioavailability of the liver and intestines, which is not conducive to improving the ability of patients to seek medical treatment, and the physical hazards of staff, etc. Problems, to achieve the effect of being conducive to labor protection and environmental protection, improving bioavailability, and low labor intensity
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[0025] Now with several groups of specific examples, the preparation method of Maodongqing dripping pills of the present invention will be further described.
[0026] Group 1: Tests with a single matrix
[0027] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredient of the traditional Chinese medicine Maodongqing is pre-prepared for use;
[0028] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;
[0029] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0030] 4. Prepare according to the process given in [Preparation Method] 4-7 to obtain Maodongqing dripping pills of different specifications.
[0031] [test results]
[0032] Experiment 1: In order to observe the difference in quali...
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