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Transmission system for medicine containing trehalose and hyaluronic acid in use for curing burn and preparing method

A technology of delivery system and hyaluronic acid, which is applied in burn drug delivery system and its various fields, can solve the problem of not showing anti-drying, achieve the effects of reducing toxic and side effects, improving hydration, and improving the ability to adapt to the environment

Inactive Publication Date: 2007-03-07
OCEAN UNIV OF CHINA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the hyaluronic acid and cellulose ether compounds in the experiment did not show anti-drying properties.

Method used

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  • Transmission system for medicine containing trehalose and hyaluronic acid in use for curing burn and preparing method
  • Transmission system for medicine containing trehalose and hyaluronic acid in use for curing burn and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1 of the present invention (a kind of cream that can be used for burns):

[0035] The medicine delivery system for burns of the present invention comprises 100 grams of trehalose 6.5 grams, sodium hyaluronate 1.5 grams, silver sulfadiazine 2.0 grams, cetyl alcohol 9 grams, liquid paraffin 6 grams, white petrolatum 14 grams, lauryl Sodium sulfate 1g, appropriate amount of glycerin, appropriate amount of sodium chloride, appropriate amount of ethylparaben, and the rest is purified water. Make cream according to conventional method.

Embodiment 2

[0036] Embodiment 2 of the present invention (a kind of solution that can be used for burns):

[0037] The medicine delivery system for burns of the present invention contains 100 milliliters of trehalose 1.5 grams, sodium hyaluronate 0.30 grams, sodium chloride 0.70 grams, an appropriate amount of ethylparaben, and the rest is purified water. Prepare the solution according to the conventional method.

Embodiment 3

[0038] Embodiment 3 of the present invention ((a kind of solution that can be used for burns):

[0039] The medicine delivery system for burns of the present invention contains, in 100 ml, 1.5 grams of trehalose, 0.10 grams of sodium hyaluronate, 3 grams of amphotericin B, an appropriate amount of sodium chloride, and the rest is purified water. Prepare the solution according to the conventional method.

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PUM

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Abstract

A burn medicine delivery system for treating burn is prepared from trehalase, hyaluronic acid, and medicinal additive.

Description

Technical field: [0001] The invention belongs to the technical field of pharmaceuticals, and relates to a drug delivery system for burns containing trehalose (English: trehalose) and hyaluronic acid (English: hyaluronic acid, also known as hyaluronic acid) and its preparation methods . Background technique: [0002] Burn (burn) refers to tissue damage caused by heat, chemical substances, electric energy, and radiation, mainly referring to damage to the skin, mucous membranes, soft tissues, and deep parts including bones and internal organs. Among them, the damage caused by heat energy, including hot liquid (water, soup, oil, etc.), steam, high-temperature gas, flame, hot metal, etc., is called thermal injury (thermal injury): while thermal injury caused by hot liquid and steam , called scald (scald), so burn includes thermal injury (including scald), chemical burn (chemical burn), electric burn (electric burn) and radiation burn (ratiation burn). Burns are very common in p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/36A61P17/00
CPCA61K47/36A61P17/00A61P17/02
Inventor 凌沛学管华诗
Owner OCEAN UNIV OF CHINA
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