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Acne eliminating tablet and its preparing process

A technology for eliminating acne tablets and making soft materials, which is applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, aluminum/calcium/magnesium active ingredients, etc. Delay and other problems, to achieve the effect of improving drug efficacy, improving bioavailability, scientific composition and content

Inactive Publication Date: 2007-06-27
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a preparation method of Xiaocuo Tablets, which solves the shortcomings of Xiaocuo Pills, such as slow disintegration, slow curative effect and difficult quality control.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Take Cimicifuga 72g, Bupleurum 227g, Wild Chrysanthemum 171g, Scutellaria baicalensis 213g, Scrophulariaceae 298g, Daqingye 298g, Honeysuckle 213g, Prunella vulgaris 171g, add 70% ethanol, the amount of ethanol is 8 times the total weight of the above raw materials , reflux extraction 2 to 3 times, each time for 2 hours, the extracts were filtered, combined, and ethanol was recovered under reduced pressure, the solution was concentrated to a relative density of 1.25 to 1.40, and set aside; another 298g of gentian, 256g of Radix Ophiopogon japonicus, 298g of dendrobium, and raw gypsum 426g, bamboo 142g, dandelion 213g, light bamboo leaves 171g, comfrey 171g, add 10 times the amount of water, soak for 1 hour, decoct 2-3 times for 2 hours each time, filter, combine the filtrates, and concentrate under reduced pressure to relative Density 1.10-1.30, add ethanol until the alcohol content reaches 60%, refrigerate for 24 hours, filter, recover ethanol, concentrate the solution ...

Embodiment 2

[0077] Take Cimicifuga 80g, Bupleurum 196g, Wild Chrysanthemum 164g, Scutellaria baicalensis 240g, Scrophulariaceae 320g, Daqingye 320g, Honeysuckle 196g, Prunella vulgaris 164g, add ethanol with a concentration of 75%, the amount of ethanol is 7 times of the total weight of the above raw materials , reflux extraction 2 to 3 times, each time for 4 hours, the extracts were filtered, combined, and the ethanol was recovered under reduced pressure, the solution was concentrated to a relative density of 1.25 to 1.40, and set aside; another 320g of Gentiana, 229g of Radix Ophiopogon japonicus, 320g of Dendrobium, and raw gypsum 393g, 131g bamboo, 196g dandelion, 200g light bamboo leaves, 200g comfrey, add 8 times the amount of water, soak for 1.5 hours, decoct 2-3 times, 1 hour each time, filter, combine the filtrates, concentrate under reduced pressure to relative Density 1.10-1.30, add ethanol until the alcohol content reaches 70%, refrigerate for 24 hours, filter, recover ethanol,...

Embodiment 3

[0079]Take Cimicifuga 65g, Bupleurum 240g, Wild Chrysanthemum 200g, Scutellaria baicalensis 196g, Scrophulariaceae 262g, Daqingye 262g, Honeysuckle 240g, Prunella vulgaris 200g, add ethanol with a concentration of 65%, and the amount of ethanol is 9 times the total weight of the above raw materials , reflux extraction 2 to 3 times, each time for 1 hour, the extracts were filtered, combined, and ethanol was recovered under reduced pressure, the solution was concentrated to a relative density of 1.25 to 1.40, and set aside; another 262g of Gentiana, 280g of Radix Ophiopogon japonicus, 262g of Dendrobium, and raw gypsum 480g, bamboo 160g, dandelion 240g, light bamboo leaves 164g, comfrey 164g, add 12 times the amount of water, soak for 0.5 hours, decoct 2-3 times, 3 hours each time, filter, combine the filtrates, concentrate under reduced pressure to relative Density 1.10-1.30, add ethanol until the alcohol content reaches 50%, refrigerate for 24 hours, filter, recover ethanol, co...

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PUM

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Abstract

The present invention discloses one kind of acne eliminating tablet and its preparation process. The acne eliminating tablet is prepared with cimicifuga rhizome, bupleurum root, ophiopogon root, wild chrysanthemum flower, skullcap root and other 11 kinds of Chinese medicinal materials and lubricant. The preparation process includes the steps of alcohol refluxing partial Chinese medicinal materials and filtering the extracted liquid; decocting the other Chinese medicinal materials and concentration to obtain dense ointment; mixing the filtrate and the ointment, drying, crushing to obtain fine powder, pelletizing, tabletting, coating and others. The acne eliminating tablet has high bioavailability and high treating effect.

Description

technical field [0001] The invention belongs to the field of medicines and preparation technology thereof, and in particular relates to a preparation method of Xiaocuo tablets. Background technique [0002] Acne is a chronic disease of the sebaceous glands. It mainly occurs on the face, chest and back of young men and women. It can form acne, papules, pustules, nodules, cysts and other damages. Squeezing and touching, repeated infection is accompanied by proliferative inflammation of local skin tissue, resulting in the formation of "sitting paralysis". The incidence rate among young people is about 10-30%, and the recurrence rate is high. It is a common disease and frequently-occurring disease that affects beauty. [0003] At present, the main treatment is heat-clearing and detoxifying. One of the better curative effect "Xiaocuo Pills" is a pill made of sixteen traditional Chinese medicines. Its disadvantages are slow disintegration and slow curative effect, and it is diffi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K36/8984A61K36/8968A61K36/808A61K36/71A61K36/539A61K36/536A61K36/515A61K36/35A61K36/30A61K36/288A61K36/28A61K36/233A61K36/19A61K33/06A61K9/20A61P17/10
Inventor 李维凤牛晓峰吴凡李延曾爱国
Owner XI AN JIAOTONG UNIV