Ursine fat injection emulsion, and its prepn. method
A technology of seal oil and emulsion, which can be applied in directions such as pharmaceutical formulations, emulsion delivery, and non-active ingredients medical preparations, etc., can solve the problems of unsatisfactory properties of raw material oil and low content of unsaturated fatty acids, etc.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0157] Prepare 1000 grams of seal oil injection emulsion, comprising the following steps:
[0158] 1. Take 100 grams of water for injection, heat it to 40°C, add 2 grams of F68 and 12 grams of egg yolk lecithin, and crush it with an ultrasonic crusher until it becomes a uniform phospholipid dispersion;
[0159] 2. Dissolve 10 grams of glycerin with 40 grams of water for injection, filter through a 0.2 μm membrane and add to the phospholipid dispersion;
[0160] 3. Take 210 grams of purified fur seal oil. Dissolve 0.05 grams of vitamin E in oil, filter it through a 0.2 μm membrane and heat it to 40°C, then slowly add it into the phospholipid dispersion, ultrasonic emulsification while adding, the speed of adding oil is such that no visible oil droplets appear on the water surface. After the oil is added, add water for injection to 1000 grams of emulsion, and then continue ultrasonic emulsification for 5 minutes to form a uniform primary emulsion;
[0161] 4. G for primary emu...
Embodiment 2
[0166] Prepare 1000 grams of seal oil injection emulsion, comprising the following steps:
[0167] 1. Take 100 grams of water for injection, heat it to 55°C, add 1.2% egg yolk lecithin, and crush it with an ultrasonic breaker until it becomes a uniform phospholipid dispersion;
[0168] 2. Dissolve 25 grams of sorbitol and 3 grams of sodium oleate for injection with 200 grams of water for injection, filter through a 0.2 μm membrane and add to the phospholipid dispersion;
[0169] 3. Take 300 grams of purified seal oil, dissolve 0.1 grams of di-tert-butyl p-cresol in the oil, filter through a 0.2 μm membrane and heat to 55 ° C, then slowly add it into the phospholipid dispersion, and ultrasonic emulsify while adding, The speed of adding the oil is limited to the fact that there are no visible oil droplets on the water surface. After the oil is added, add water for injection to 1000 grams of emulsion, and then continue ultrasonic emulsification for about 10 minutes to form a unif...
Embodiment 3
[0175] Prepare 1000 grams of seal oil injection emulsion, comprising the following steps:
[0176] 1. Take 60 grams of water for injection, heat it to 70°C, add 6 grams of egg yolk lecithin, and crush it with an ultrasonic crusher until it becomes a uniform phospholipid dispersion;
[0177] 2. Dissolve 50 g of glucose and 0.1 g of cholic acid in 100 g of water for injection, filter through a 0.2 μm membrane and add to the phospholipid dispersion;
[0178] 3. Take 500 grams of purified seal oil, dissolve 0.2 grams of p-hydroxytert-butyl anisole in the oil, filter it through a 0.2 μm membrane and heat it to 70°C, then slowly add it into the phospholipid dispersion, and ultrasonic emulsify while adding, The speed of adding the oil is limited to the fact that there are no visible oil droplets on the water surface. After the oil is added, add water for injection to 1000 grams of emulsion, and then continue ultrasonic emulsification for about 30 minutes to form a uniform primary emu...
PUM
Property | Measurement | Unit |
---|---|---|
diameter | aaaaa | aaaaa |
particle diameter | aaaaa | aaaaa |
particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com