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Sulfur absorbent for reducing onion or garlic breath odor

A composition and amino acid technology, which can be used in medical preparations containing active ingredients, other chemical processes, chewing gum, etc., and can solve problems such as changing taste

Inactive Publication Date: 2002-09-11
PI KJU KHLDG INK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A common problem with most of these compositions and methods is that they alter the taste of food and oral medications when they are incorporated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Synthesis of Cystine-Copper Complex

[0027] A cystine solution was prepared by mixing 40ml of water with 4.42g of cystine hydrochloride and adjusted to pH 10 with 1M NaOH. A drop of 1M copper sulfate was added and oxygen was bubbled through the solution at room temperature until the purple solution turned green. Adjust the pH to 6-8 with hydrochloric acid.

[0028] A metal salt solution was prepared by mixing 4.32 g copper chloride dihydrate with 10 ml water. When the metal and amino acid solutions are slowly mixed with stirring, an insoluble complex is formed immediately. The pH was adjusted to 6-8 with 1M sodium hydroxide. The complex was washed with water and the complex was removed by filtration through a Buchner funnel. The complex was dried overnight in an oven at 60°C.

Embodiment 2

[0030] Synthesis of Cystine-Copper Complex Supported on Silica Gel

[0031] The aqueous suspension (5g in 50ml) of the cystine-copper complex of the embodiment was mixed with dilute sodium silicate solution (200ml sodium silicate (3:22 ​​SiO 2 :Na 2 (0w / w, 37.6% solids) + 200ml water) were mixed, and about 20ml of 8N sulfuric acid was quickly added thereto and mixed. The suspension gelled within 3 minutes. After incubation at room temperature for 60 minutes, the solid was broken up, washed with water to a conductivity of 650 microSiemens, dried at 60°C, and ground to a powder.

Embodiment 3

[0033] Synthesis of Polystyrene-based Cation Exchanger-Copper Complex

[0034] Dowex® 50W (H + Type, 200-400 mesh) aliquot (2.0 g) and 50 ml of 0.1 M copper chloride were stirred at room temperature for 2 minutes. The pH was adjusted to neutral with 10N and 1N sodium hydroxide and stirring was continued for a further 10 minutes. The green solid was then filtered off, washed 3 times with 500 ml of water, and dried overnight at 60°C.

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PUM

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Abstract

Compositions for adsorbing sulfur-containing compounds and eliminating or reducing odors associated with the ingestion of foods or medicines causing sulfur odor, such as garlic and onions, contain a metal complex of a substrate and a ligand. The complex may be contained in a carrier, such as a silica gel, and has low solubility in an aqueous environment. The ligand of the compositions may comprise an amino acid containing sulfur, nitrogen, or a carboxylic acid, such as cystine, and the substrate is a metal which may be copper, zinc, or iron.

Description

technical field [0001] The present invention generally relates to compositions and methods for eliminating or reducing breath odors caused by sulfur-containing compounds that are produced upon ingestion of foods and pharmaceuticals. More specifically, the present invention relates to the elimination or reduction of breath odor by adsorption of sulfur-containing compounds and their components and derivatives contained in foods consisting of garlic or onions. Background of the invention [0002] Many chemicals and foods contain sulfur compounds that have strong odors. Ingestion of these chemicals or foods often produces unpleasant breath odors that originate from the ingested compound or its metabolites, or both. Garlic and onions are foods that have an extremely strong sulfur odor and cause an extremely bad breath odor. [0003] Garlic and other foods and chemicals contain or produce various sulfur compounds, including allicin, allicin, and diallyl ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23G4/00A61K8/00A61K8/19A61K8/25A61K8/44A61K8/46A61K8/81A61Q11/00A61Q15/00B01J20/22
CPCA61K8/19A61K8/447A61K8/8117A61K2800/58A61K2800/92A61Q11/00A61Q15/00A61K8/23
Inventor 肯尼思·A·伯格
Owner PI KJU KHLDG INK