Catalyst for cyclopropanizing reaction of olefine and its preparing process

Abstract

A carried catalyst used for cyclopropanizing 2,5-dimethyl-2,4-hexadiene contains the active component (20-90%) chosen from Fe, Ca, Ni, Ca, Zn, Cr, Mo or Ti, the assistant (0.1-5%) chosen from L, Na or K, and the carrier chosen from alumina silica gel and activated carbon. It is prepared through premodifying carrier, and immersing while adding active component and the organic compound containing hydroxy or carboxyl group and oxygen. Its advantages are low dosage, high output rate, little coking and easy separation.

Description

technical field

[0001] The invention relates to a supported catalyst, in particular to a supported catalyst for 2,5-dimethyl-2,4-hexadiene cyclopropanation reaction. Specifically, in the presence of the catalyst, the cyclopropanation reaction of olefin and diazoacetate is used to prepare the first methyl chrysanthemate, the first ethyl chrysanthemate and the like. The process has the characteristics of high reaction yield, less coking, less catalyst consumption, and easy separation of catalyst and reaction system. technical background

[0002] Catalytic cyclopropanation of olefins is an important method for the synthesis of a class of organic intermediates, and is widely used in the synthesis of pharmaceutical and pesticide industries, such as the synthesis of the first methyl chrysanthemum acid, the first ethyl chrysanthemum acid, and permethrin Methyl ester, ethyl permethrin, etc. Most of the synthetic methods currently used are synthesized by homogeneous catalytic metho...