Mangiferin preparation and production thereof

A production method and mangiferin technology, which are applied to the preparation of mango total glycosides and the field of production thereof, can solve the problem that mango leaves or almond leaves are not found, and achieve the effects of low toxicity, high toxicity and low dosage.

A production method and mangiferin technology, which are applied to the preparation of mango total glycosides and the field of production thereof, can solve the problem that mango leaves or almond leaves are not found, and achieve the effects of low toxicity, high toxicity and low dosage.

CN1490014AInactive Publication Date: 2004-04-21田东县天然植物制品厂

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] 1. Preparation of "Mangosides"

[0022] During the production, the active ingredient "mangiferin" which is effective in relieving cough and eliminating phlegm is extracted from mango leaves or almond leaves by common pharmaceutical techniques and methods. The design of the extraction process is based on the principle of extracting the effective parts for relieving cough and eliminating phlegm, that is, the main component of the final "total mangiferin" is mangiferin, and sometimes it may contain one or more of the following components: isomangiferin, high mangiferin glycosides, neomangiferin and gallic acid. Mango leaves and almond leaves can be dried or fresh.

[0023] method one

[0024] Dried mango leaves were processed into pieces and extracted twice with 50% ethanol aqueous solution under reflux for 2 hours each time. Add 10 times the amount of 50% ethanol aqueous solution for the first time, and add 8 times the amount of 50% ethanol aqueous solution for the sec...

example 1

[0035] Add appropriate amount of starch, granulate, and press into tablets, the weight of the plain tablet is 0.3g, and each tablet is equivalent to 10g of crude drug (dried mango leaf or dried almond leaf).

example 2

[0037] The "mangototal glucosides" obtained in the above method 2 is crushed and directly packed into 0 capsules without adding auxiliary materials. Each capsule is equivalent to 10g of raw medicinal materials (dried mango leaves or dried almond leaves).

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Abstract

An orally applied chimonin preparation for relieving cough and dispelling phlegm is prepared from mango leaf or almond leaf through extracting. Its advantage is high curative effect.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation with antitussive and expectorant effects and a production method thereof. Background technique: [0002] Mango (Mangifera indica linn) and almond (Mangifera persiciformis C.Y.Wuet T.L.Ming) are both tropical and subtropical fruit trees, widely distributed in my country's Hainan, Guangxi, Guangdong and other provinces; Guangxi Zhuang Autonomous Region is one of the main producing areas of mangoes , is also a key fruit tree in Guangxi. Tiandong County and Tianyang County in Baise Prefecture were once named "Hometown of Mango" by the Ministry of Agriculture. In my country, tens of millions of tons of mango leaves and almond leaves are burned by fruit growers as firewood every year, resulting in a great waste of resources. [0003] The composition of mango leaves and almond leaves is very similar, both contain mangiferin, isomangiferin, high mangiferin, neomangiferin and gallic acid and o...

Claims

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Application Information

Patent Timeline
21 Apr 2004
Publication
CN1490014A
IPC
A61K9/00; A61K31/7048; A61P11/10; A61P11/14
Inventors
黄福满