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Yang-strengthening solid Xianrong prepn and its prepn process

A technology of solid preparation and antler mushroom, which is applied in the field of antler mushroom aphrodisiac solid preparation and its preparation, can solve the problems of affecting the safe use of preparation patients, lack of safe and efficient drugs, poor drug stability, etc. Easy to produce and take

Active Publication Date: 2004-11-24
上海海虹实业(集团)巢湖今辰药业有限公司
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  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is a lack of safe, efficient, and long-term medications for the treatment of such diseases in modern chemical drugs. It is important to carry forward the traditional advantages of traditional Chinese medicine and develop traditional Chinese medicine preparations with stable preparations, safe medication, accurate dosage, controllable quality, and reliable curative effect. significance
[0003] The existing traditional Chinese medicine preparations are liquid oral liquids with poor drug stability; they contain preservatives, refined honey and a large amount of sucrose. The intake of preservatives and too much sugar is not good for the human body and affects the safety of the preparations for some patients. Use; especially for patients suffering from certain sugar-avoiding diseases, adverse reactions such as hyperglycemia will also occur

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Preparation of Xianrong Zhuangyang Chewable Tablets

[0027] 1. Weigh 12.5g of velvet antler (hair removed), 25g of curculigo, 50g of epimedium, 25g of Morinda officinalis (salt), 25g of Cistanche, 50g of medlar, 10g of Acanthopanax extract, 50g of Polygonum multiflorum (made of) .

[0028] 2. For the above eight flavors, take Polygonum multiflorum, Epimedium, Morinda officinalis, Lycium barbarum, Cistanche, and curculigo with 8 times the amount of 35% ethanol for reflux extraction twice, the first time is 6 hours, the second time is 4 hours, combined extraction liquid, filtered, and the filtrate was concentrated to an appropriate amount, then added ethanol, stirred, allowed to stand, filtered, and recovered ethanol to obtain a concentrated solution A with a relative density of 1.06 to 1.12 at 50°C;

[0029] 3. Put the velvet antler in the pot and steam for 30-40 minutes, take out the slices, soak with 10 times the amount of 40% ethanol in an appropriate amount for mor...

Embodiment 2

[0030] Example 2: Preparation of Xianrong Zhuangyang Tablets

[0031] The preparation process is the same as in Example 1, except that only 60 g of dextrin as a forming agent is added in the above step 4. Stir evenly, filter, pass hot air in the spray state, and carry out spray drying. The temperature of the hot air inlet is 170-180°C, and the temperature of the outlet air is 70-80°C. The material is dry-granulated at a temperature of ≤60°C. granules to obtain 70 g of brown-yellow granules, which are compressed into 200 tablets.

Embodiment 3

[0032] Example 3: Preparation of Xianrong Zhuangyang Capsules

[0033] The preparation process is the same as in Example 2, except that the granules are filled into capsules to obtain 200 capsules.

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Abstract

The Yang-strengthening solid medicine preparation, named Xianrong, is prepared with pilose antler, curculigo rhizome, epimedium, morinda root, wolfberry fruit and other three kinds of Chinese medicinal materials; and it features its supplementary material including beta-cyclodextrin, corrective stevioside or proteoglycan and plasticizer selected from mannitol, sorbic alcohol, xylitol, dextrin and lactose oligomer and the spray drying and dry pelletizing capable of maintaining the effective component completely and suitable for continuous GMP production. The medicine contains no cane sugar and preservative, is safe, without side effect, and has many other advantages.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine for invigorating kidney and strengthening yang, treating physical deficiency, impotence and kidney cold and a preparation method thereof. Background technique: [0002] With the acceleration of the pace of society and the increase of work pressure, male sexual function decline, limb weakness, backache and leg pain, memory loss and other diseases have become common and frequently-occurring diseases in men. The research and application of this type of drugs are becoming more and more important. However, there is a lack of safe, efficient, and long-term medications for the treatment of such diseases in modern chemical drugs. It is important to carry forward the traditional advantages of traditional Chinese medicine and develop traditional Chinese medicine preparations with stable preparations, safe medication, accurate dosage, controllable quality, and reliable curative effect. significance. [000...

Claims

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Application Information

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IPC IPC(8): A61P1/14A61P15/08
Inventor 濮桂宝李来润娄贯平张日武范弋陶良宝任军蒋小云
Owner 上海海虹实业(集团)巢湖今辰药业有限公司
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