Aretificial nerve canula material of slow operating complex type poly lactic acid and preparation method

A technology of artificial nerve and polylactic acid, applied in medical science, prosthesis, etc.
CN1562383AInactive Publication Date: 2005-01-12WUHAN UNIV OF TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
WUHAN UNIV OF TECH
Publication Date
2005-01-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

A slowly-releasing artificial nerve canal for repairing nerve is prepared through dissolving the bio absorptive polylactic acid in organic solvent adding hydroxy apatite nanoparticles and freeze-dried nerve growth factor (NGF) powder, ultrasonic dispersing and volatilizing solvent to obtain milliporous canal.
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Description

technical field

[0001] The invention relates to a composite slow-release artificial nerve guide material and preparation technology for repairing and regenerating human nerve damage. Background technique

[0002] Peripheral nerve injuries and defects are common in clinical practice, so far, the therapeutic effect is not satisfactory. How to improve the curative effect is still an important issue that needs further research.

[0003] The main problems affecting nerve repair and regeneration are limited sources of transplanted nerves, damage to the donor site, slow nerve regeneration, and poor regeneration quality. There have been many studies on nerve substitutes in the past, including autologous blood vessels, muscles, tendons, fascia, and synthetic non-absorbable and absorbable nerve bridge catheters. These materials and methods have achieved different therapeutic effects in animal experiments, and some materials have been used in clinical research reports. But in genera...

Claims

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