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Composite effervescent preparation containing soya isoflavone

A technology for soybean isoflavones and effervescent preparations, which is applied in the directions of medical preparations containing active ingredients, pill delivery, and drug combinations, can solve problems such as poor water solubility, reduced absorption, etc., to improve stability, accelerate human absorption, and facilitate The effect of taking

Inactive Publication Date: 2005-03-09
博凯药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to poor water solubility, the body's absorption of it is reduced

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Compound Soy Isoflavone Effervescent Tablets

[0013] Formula: Each tablet contains:

[0014] Soy Isoflavones (60%) 100mg

[0015] Citric acid 1800mg

[0016] Vitamin C 300mg

[0017] Vitamin E 50IU

[0018] Sodium bicarbonate 1200mg

[0019] Polyvinylpyrrolidone (PVP) 50mg

[0020] Sweetener 100mg

[0021] The above raw materials are pulverized, passed through a 80-120 mesh sieve, weighed, mixed, granulated, dried and then blended, and tableted. The weight of the tablet is 4g, and the content of soybean isoflavones in each tablet is 60mg. One tablet per day. When taking it, take the effervescent tablet out of the packaging bag, put it into a glass of drinking water, it will dissolve within 3 minutes, and you can drink it.

Embodiment 2

[0023] Compound Soy Isoflavone Effervescent Tablets

[0024] Formula: Each tablet contains:

[0025] Soy Isoflavones (60%) 100mg

[0026] Vitamin D 100IU

[0027] Calcium Lactate 300mg

[0028] Zinc Lactate 50mg

[0029] Citric acid 1800mg

[0030] Malic acid 100mg

[0031] Sodium bicarbonate 1200mg

[0032] Polyvinylpyrrolidone (PVP) 50mg

[0033] Sweetener 150mg

[0034] Processed into effervescent tablets according to the process of Example 1, the tablet weight is 3.8g, take 1-2 tablets every day.

Embodiment 3

[0036] Compound soybean isoflavone effervescent granules

[0037] Formula: Each bag of compound soybean isoflavone effervescent granules contains:

[0038] Soy Isoflavones (40%) 200mg

[0039] Vitamin C 500mg

[0040] Vitamin E 50IU

[0041] Vitamin B 6 50mg

[0042] Folic Acid 5mg

[0043] Vitamin D 100IU

[0044] Calcium Ascorbate 200mg

[0045] L-Arginine 1000mg

[0046] Citric acid 1800mg

[0047] Malic acid 200mg

[0048] Sodium bicarbonate 1200mg

[0049] Sweetener 600mg

[0050] Appropriate amount of adhesive

[0051] Crush the above raw materials, pass through a 80-mesh sieve, weigh, fully mix, granulate, dry below 70°C, and granulate until the water content drops below 2%. Select granules between 12 and 14 mesh and pack 6g per bag. Take 1-2 bags a day.

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PUM

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Abstract

A composite effervescent medicine or health food in the form of tablet or particle for preventing osteoporosis, climacteric syndrome and cardiovascular disease of woman is prepared from soybean isoflavone, vitamines, amino acids, trace elements, effervescent agent, adhesive and lubricant.

Description

technical field [0001] The invention belongs to a new type of quick-release effervescent dosage form of soybean isoflavone compound preparation, which can improve the stability of bioactive ingredients, accelerate human body absorption, and is convenient to take, and is especially suitable for bone transport, cardiovascular disease, menopausal syndrome and the health of adult women health care. Background technique [0002] Soy isoflavones (Isoflavones of Soybeen) are mainly derived from the pods of legumes, and the two biologically active components are mainly genistein (also known as genistein) and daidgein. Natural soybean isoflavones are divided into two types: free aglycone (Aglycon) and combined glycoside (Glucosides). [0003] The aglycones of soybean isoflavones are generally insoluble or insoluble in water, and the solubility of conjugated glycosides in water is enhanced, and they can be dissolved in hot water. Due to poor water solubility, it reduces the body's a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/46A61K31/352A61P9/10A61P15/12A61P19/10
CPCA61K9/0007
Inventor 许平辉叶新岚胡晓娟李会涛张会敏雷天乾赵鸿毅
Owner 博凯药业有限公司