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Modular solid state fermentation reactor

A solid-state fermentation and reactor technology, applied in the field of modular solid-state fermentation reactors with variable volume, can solve the problems of product yield, quality decline, cumbersome multi-step operation, and the inability to realize precise control of growth conditions, so as to prevent bacterial contamination, extract handy effects

Inactive Publication Date: 2005-03-23
INST OF PROCESS ENG CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

So far, solid-state fermentation still requires cumbersome multi-step operations, and fermentation in an open environment cannot achieve precise control of growth conditions, resulting in reduced product yield and quality

Method used

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  • Modular solid state fermentation reactor
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  • Modular solid state fermentation reactor

Examples

Experimental program
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Effect test

Embodiment

[0039] See figure 1 -5. Three-layer solid-state fermentation reactor, diameter 100cm, module height 8cm, microorganism: red yeast rice, raw material: indica rice. This example does not include the extraction of the active substance.

[0040] At first need to add 14.6kg (dry weight) soaked indica rice in each clean module 3, then install all modules 3 together to form stack 4, at this moment the inside of the reactor is isolated from the external environment. Sterilization fluid such as steam or ozone flows into the distribution ring from the distribution port, enters the transmission channel 9, and releases the fluid into the module through the hole 11 on the transmission channel. At the same time, steam is passed into the non-transport channel 10 to heat the reactor to an appropriate sterilization temperature (121°C for steam, 50°C for ethylene oxide). After sterilization, cooling water flows into the non-transmission channel 10 to cool the matrix, and the matrix enters th...

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Abstract

The invention relates to a modularized solid-state fermentation reactor, composed of one or many singly-operable modules, mixed arm and concentric shaft; the module is composed of annular transmission channel and a cylindrical outer wall, and a pipeline system with mutually-separated transmission channel and non-transmission channel is arranged on a basal disc, where the non-transmission channel carries heat conductivity fluid and the transmission channel feeds water, nutrient substance, oxygen gas, extract and so on to the modules; the concentric shaft is installed with the mixed arm, which keeps rotating around the mixed arm to blend the materials. It closely operates, the distribution of fed liquid material is uniform, the reaction conditions are accurately controlled according to the change of environmental parameters, and it provides a method of in-situ extracting the needed microbe product in a reactor.

Description

technical field [0001] The invention belongs to the field of solid-state fermentation reactors, in particular to a modular volume-variable solid-state fermentation reactor. Background technique [0002] Solid-state fermentation is mostly used in food production and has a history of hundreds of years. It refers to the technology of microorganisms growing on moist solid substrates. In recent years, there has been interest in the ability of solid-state fermentation to produce bioactive substances. Compared with liquid fermentation, solid-state fermentation has high yield and low cost. However, due to the low design level of solid-state fermentation equipment, its industrial application is still limited. [0003] Solid-state fermentation equipment can be divided into two categories: static and dynamic. In the static system, the solid substrate remains unchanged throughout the fermentation process. Typical static systems include boxes, trays, plates, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00
CPCC12M21/16C12M23/44C12M27/06
Inventor 李浩然杜竹玮
Owner INST OF PROCESS ENG CHINESE ACAD OF SCI
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