New crystalline technology of fructose-1, 6-trisodium diphosphate

A trisodium diphosphate salt and a new process technology, which is applied in the direction of sugar derivatives, sugar derivatives, esterified saccharides, etc., can solve the problems of uneven product particle size and poor stability, and achieve easy control operation and improved Good uniformity and repeatability
CN1651448AInactive Publication Date: 2005-08-10NANJING UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NANJING UNIV OF TECH
Publication Date
2005-08-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

A process for crystallizing pectose-1,6-trisodium biphosphate includes such steps as slowly and proportionally adding sodium acetate and alcohol to FDP solution, stirring at 20-40 deg.C while crystallizing, filtering, washing with alcohol and vacuum drying.
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Description

Technical field:

[0001] The present invention relates to the production of crystalline form fructose-1,6-diphosphate trisodium salt (FDPNa) by utilizing fructose-1,6-diphosphate aqueous solution 3 H·8H 2 O) the new method and use this method to prepare fructose-1,6-diphosphate trisodium salt injection, application clinically obviously reduces the stimulation of medicine to muscles and blood vessels. technical background:

[0002] Fructose 1,6-diphosphate (FDP) is also called Harden Young's ester (esterof Harden Young). It is an important intracellular metabolite and an intermediate product in the glycolytic metabolic pathway in humans. It can directly regulate many metabolic pathways and can be regarded as a metabolic regulator, especially playing an important role in energy metabolism and regulating certain enzyme activities. Clinically, it can regulate the activity of several enzymes in glucose metabolism, restore and improve cell metabolism at the molecular level, act ...

Claims

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