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Preparation method of calcium phosphate composite bone cement

A technology of bone cement and calcium phosphate, which is applied in the field of preparation of calcium phosphate composite bone cement, can solve the problems of large and only 26-28% reduction, and achieve the effects of low cost, simple process and improved compressive strength

Inactive Publication Date: 2005-08-24
WUHAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Ishikawa uses two methods of increasing the solid-liquid ratio and pressurizing the CPC in the mold (173Mpa) during the curing process to reduce the porosity to increase the strength of the CPC cured body. It is found that the porosity can only be reduced by 26-28% at the maximum, and the flexural strength The maximum can only be increased by 50%, and the advantage of CPC in clinical application that can be shaped arbitrarily is lost

Method used

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  • Preparation method of calcium phosphate composite bone cement
  • Preparation method of calcium phosphate composite bone cement
  • Preparation method of calcium phosphate composite bone cement

Examples

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Effect test

Embodiment 1

[0021] A preparation method of calcium phosphate composite bone cement, such as figure 1 shown, including the following steps:

[0022] 1). Surface treatment of carbon fiber: first, oxidize the carbon fiber with sodium hydroxide solution to increase the oxygen content on the surface of the carbon fiber; use a diameter of 12 μm, a tensile strength of 80-120kgf / mm, and a Young's modulus of 5-10 ×10 3 kg / mm 2 Clean the carbon fiber with distilled water, dry it, then immerse the dried carbon fiber in a NaOH solution with a concentration of 2-10%, and heat it at 80°C for 2 hours; rinse the treated carbon fiber with distilled water, and heat it at 150°C After drying, the carbon fiber is cut into 1mm-8mm for later use (according to aspect ratio 125-625). Such as figure 2 As shown, after being treated with NaOH solution, the main peak broadened, and the small peak appeared and moved to the direction of high binding energy. The greater the concentration of NaOH, the more obvious t...

Embodiment 2

[0040] A preparation method of calcium phosphate composite bone cement, such as figure 1 shown, including the following steps:

[0041] 1). Surface treatment of carbon fiber: first, oxidize the carbon fiber with sodium hydroxide solution to increase the oxygen content on the surface of the carbon fiber; use a diameter of 12 μm, a tensile strength of 80-120kgf / mm, and a Young's modulus of 5-10 ×10 3 kg / mm 2 Clean the carbon fiber with distilled water, dry it, then immerse the dried carbon fiber in a NaOH solution with a concentration of 2-10%, and heat it at 80°C for 2 hours; rinse the treated carbon fiber with distilled water, and heat it at 150°C Dry, cut the carbon fiber into 1mm-8mm for later use, carbon fiber diameter ratio=125-625;

[0042] 2). Preparation of composite powder: fully mix tetracalcium phosphate and anhydrous calcium hydrogen phosphate at a Ca / P molar ratio of 1.67 to obtain calcium phosphate bone cement;

[0043]0.05-2% of the carbon fiber obtained in t...

Embodiment 3

[0052] A preparation method of calcium phosphate composite bone cement, such as figure 1 shown, including the following steps:

[0053] 1). Surface treatment of carbon fiber: first, oxidize the carbon fiber with sodium hydroxide solution to increase the oxygen content on the surface of the carbon fiber; use a diameter of 12 μm, a tensile strength of 80-120kgf / mm, and a Young's modulus of 5-10 ×10 3 kg / mm 2 Clean the carbon fiber with distilled water, dry it, then immerse the dried carbon fiber in a NaOH solution with a concentration of 2-10%, and heat it at 80°C for 2 hours; rinse the treated carbon fiber with distilled water, and heat it at 150°C Dry, cut the carbon fiber into 1mm-12mm for later use, carbon fiber aspect ratio=80-1000;

[0054] 2). Preparation of composite powder: fully mix α-tricalcium phosphate, calcium dihydrogen phosphate and calcium carbonate at a Ca / P molar ratio of 1.60 to obtain calcium phosphate bone cement;

[0055] 0.05-2% of the carbon fiber ob...

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Abstract

A composite calcium phosphate cement for preparing artificial bone is prepared through immersing carbon fibres in NaOH solution, heating at 70-90 deg.C for 2-3 hr, flushing, drying, shearing short, proportionally mixing it with calcium phosphate cement, stirring to obtain composite powder, proportionally mixing it with solidifying liquid, stirring, moulding and curing.

Description

technical field [0001] The invention relates to a preparation method of a composite material containing calcium phosphate bone cement, in particular to a preparation method of a calcium phosphate composite bone cement. The calcium phosphate composite bone cement can be used as a material for filling, repairing and replacing human hard tissues. Background technique [0002] Calcium phosphate cement (CPC) is composed of powder mixed with one or more calcium phosphate salts and a solidification liquid. When used, the two are mixed in a certain proportion, and can be cured and accurately cured at room temperature, human environment and humidity. Plastic, whose composition is finally mainly converted into microporous hydroxyapatite (HAP) crystals, has good biocompatibility, and has broad application prospects in the fields of implantology and orthopedic traumatology. However, since the calcium phosphate bone cement (hardened body is a porous and brittle material), its mechanical ...

Claims

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Application Information

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IPC IPC(8): C04B14/38C04B28/34
Inventor 戴红莲李世普闫玉华王欣宇曹献英韩颖超陈晓明袁琳李建华
Owner WUHAN UNIV OF TECH
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