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Acanthopanax bark-ginseng-Chinese angelica root-astragalus root dripping pill and its preparing method

A kind of technology of Acanthopanax ginseng and Acanthopanax senticosus, which is applied in the field of oral preparations of pharmaceutical compositions, can solve the problems of low dissolution rate, unfavorable overall health level, inconvenient taking or carrying, etc., achieves faster dissolution and absorption, and is beneficial to labor protection , Improve the effect of bioavailability

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Wujiashenguiqi dripping pills of the present invention will be further described.

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of medicinal extracts: According to [Preparation Method 1], the dry extract powders containing the active ingredients of three traditional Chinese medicines such as Acanthopanax, Angelica, and Radix Astragali are prepared for use;

[0031] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Wujiashenguiqi dripping pills of di...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, manyprickle acanthopanax -ginseng -astragalus dripping pill, for treating weak health, insomnia, night sweat, soreness of the waist and knees, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost. The manyprickle acanthopanax -ginseng -astragalus dripping pill is prepared with three kinds of Chinese medicinal materials including ginseng, manyprickle acanthopanax root, angelica, astragalus root and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the functions of strengthening the body, nourishing qi and solidifying the surface, nourishing blood and nourishing blood, and is used for the treatment of diseases such as protracted illness, weakness, insomnia, spontaneous sweating, sore waist and knees, shortness of breath and heart palpitations. An oral preparation of a pharmaceutical composition prepared from the extracts of active pharmaceutical ingredients of three traditional Chinese medicines, such as Jiajia, Angelica, and Astragalus, as raw materials. Background technique [0002] According to the preparation method given in the ministerial drug standard WS3-B-0204-90, Acanthopanax ginseng Guiqijing is prepared, which has the functions of strengthening the body, nourishing qi and solidifying the surface, and nourishing blood. It is a syrup-based oral preparation for the treatment of debility, insomnia, spontaneous swea...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/14A61P25/20
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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