Flavone hippophaes drop pills and method for preparing the same
A technology of acetaloflavone and dripping pills, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problem of large differences in pill weight, quality indicators, low rounding rate of qualified products, and influence on drug use. Dosage accuracy and other issues, to achieve the effects of small differences in pill weight, safe medication, and improved bioavailability
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[0029] Now with several groups of specific examples, the preparation method of acetaloflavone dripping pills of the present invention will be further described.
[0030] [Test prescription]
[0031] 1. Raw material - acetaloflavone
[0032] 2. Base—a mixture of polyoxyl 40 stearate and polyethylene glycol, as follows:
[0033] 2.1 Polyoxyl 40 stearate: polyethylene glycol 2000 =1:1~1:10
[0034] 2.2 Polyoxyl 40 stearate: polyethylene glycol 4000 =1:1~1:10
[0035] 2.3 Polyoxyl 40 stearate: polyethylene glycol 6000 =1:1~1:10
[0036] 2.4 Polyoxyl 40 stearate: polyethylene glycol 10000 =1:1~1:10
[0037] 2.5 Polyoxyl 40 stearate: polyethylene glycol 20000 =1:1~1:10
[0038] 3. The ratio of acetaloflavone and matrix:
[0039] In g or kg as the unit, acetaloflavone: matrix = 1:1~1:9
[0040] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get aceflavone dripping pills with different specifications.
[0041] [Test content and results] ...
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