Chinese medicine injection for clearing away heat and toxic matter and its prepn process

An injection preparation, heat-clearing and detoxifying technology, applied in antiviral agents, pharmaceutical formulations, drug delivery, etc., can solve the problems of failing to meet the quality requirements of traditional Chinese medicine injections, not fully exerting the efficacy of drugs, and poor stability of injections, etc., to achieve The curative effect is rapid and significant, the quality and stability are improved, and the quality is stable

Inactive Publication Date: 2006-03-01
张正生
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The patent (application number 00114304.2) discloses a preparation method of a Chinese patent medicine for clearing heat, detoxifying and anti-infection. In this invention, honeysuckle, Folium Folium, Dandelion, and Houttuynia cordata are extracted and prepared into granules, which have the functions of clearing away heat, detoxifying and anti-infection, and have antibacterial properties. , anti-virus, anti-endotoxin, antipyretic, anti-inflammatory, immune regulation and other characteristics, it has a certain effect on wind-warm lung-heat syndrome such as cold, influenza and acu

Method used

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Examples

Experimental program
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Example Embodiment

[0073] Example 1:

[0074] (1) The composition of raw materials in parts by weight is: 250g each of honeysuckle, green leaf, dandelion, and houttuynia cordata;

[0075] (2) Take Houttuynia cordata, steam distillation, collect 1300ml initial distillate, then re-distill, collect 250ml heavy distillate, save it separately for use;

[0076] (3) Wash honeysuckle, green leaves, and dandelion, add water and decoct 2 times, 1 hour each time, combine the decoction, filter, concentrate under reduced pressure to about 200ml, set the edges, and treat with ethanol precipitation for three times, the first time The ethanol content in the solution is 60%, 80% for the second time, and 85% for the third time. The drug solution is concentrated to a relative density of 1.15-1.20 (50°C) before alcohol precipitation, and the temperature is below 15°C after alcohol precipitation. Let stand for 48 hours, filter, and concentrate the filtrate after three times of alcohol precipitation to about 50ml under r...

Example Embodiment

[0078] Example 2:

[0079] (1) The composition of raw materials in parts by weight is: 250g each of honeysuckle, green leaf, dandelion, and houttuynia cordata;

[0080] (2) Take Houttuynia cordata, steam distillation, collect 1000ml of initial distillate, then re-distill, collect 250ml of heavy distillate, save it separately for use;

[0081] (3) Wash honeysuckle, green leaves and dandelion, add water and decoc 3 times, 1 hour each time, combine the decoction, filter, concentrate under reduced pressure to about 200ml, set the edges, and treat with ethanol precipitation for three times, the first time The ethanol content in the solution is 65%, 80% for the second time, and 90% for the third time. Each time the drug solution is concentrated to a relative density of 1.15-1.20 (50°C) before alcohol precipitation, and the temperature is below 15°C after alcohol precipitation. Let stand for 48 hours, filter, and concentrate the filtrate after three times of alcohol precipitation to abou...

Example Embodiment

[0083] Example 3:

[0084] (1) The composition of raw materials in parts by weight is: 250g each of honeysuckle, green leaf, dandelion, and houttuynia cordata;

[0085](2) Take Houttuynia cordata, steam distillation, collect 1500ml of initial distillate, and then re-distill, collect 250ml of heavy distillate, save it separately for later use;

[0086] (3) Wash honeysuckle, green leaves, and dandelion, add water and decoct 2 times, 1 hour each time, combine the decoction, filter, concentrate under reduced pressure to about 200ml, set the edges, and treat with ethanol precipitation for three times, the first time The ethanol content in the solution is 60%, the second time is 75%, and the third time is 85%. The drug solution is concentrated to a relative density of 1.15-1.20 (50°C) before alcohol precipitation, and the temperature is below 15°C after alcohol precipitation. Let stand for 24 hours, filter, and concentrate the filtrate after three times of alcohol precipitation to about...

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Abstract

The Chinese medicine injection for clearing away heat and toxic material is prepared with honeysuckle, isatis leaf, dandelion and cordate houttuynia in the same proportion as material and through extractive, purification and other steps. The injection has high quality, high stability and high pharmaceutical effect.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation method of a heat-clearing and detoxifying traditional Chinese medicine injection preparation and the preparation thereof. Background technique [0002] The proportion of infectious diseases in clinical practice is very high. At present, the western medicine method of clinical treatment is mainly the application of antibacterial drugs. Due to the increase of adverse reactions caused by antibacterial drugs and the emergence of drug-resistant strains, the course of disease will be prolonged and the treatment will be ineffective in clinical treatment. And other issues. The anti-infection mechanism of traditional Chinese medicine is not directly antibacterial and bactericidal, but mainly to increase the phagocytosis index of neutrophils in blood and the level of total complement in serum, thereby enhancing the body's non-specific...

Claims

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Application Information

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IPC IPC(8): A61K36/855A61K36/78A61K36/288A61K36/355A61K9/08A61P31/04A61P31/16A61P11/00
Inventor 张正生
Owner 张正生
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