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Hepatitis treating Chinese medicine prepn and its prepn process

A technology for traditional Chinese medicine preparations and hepatitis, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, antiviral agents, etc., can solve the problems of aggravating the pain and economic burden of patients, being inconvenient for patients to take, and having frequent treatment cycles. Accurate dosage, reduction in heavy metal content, and recovery of liver function

Active Publication Date: 2006-05-17
四川泰华堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the existing traditional Chinese medicines for treating hepatitis are too limited to classical prescriptions, almost all of which are based on Bupleurum Decoction, with similarities and minor differences. Few people discover, research, and develop other Chinese medicine varieties and prescriptions suitable for treating hepatitis.
The existing traditional Chinese medicine prescriptions have better curative effect on chronic hepatitis and acute hepatitis, but the pre-treatment of acute hepatitis still mainly relies on western medicine, especially for severe hepatitis, the curative effect is not good, so that the treatment cycle is more frequent, which aggravates the suffering and economic burden of patients
In addition, the dosage forms of such drugs are usually decoctions, powders, and pills, which are not convenient for patients to take.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] (1) Take 15 parts of medicinal materials Tianzicao, 10 parts of Yin Xingcao, and 10 parts of sorrel, cut and dry the medicinal materials after cleaning; (2) add 10 times the amount of water to decoct twice, each time for 2 hours, and fry together liquid, filtered, and the filtrate was directly concentrated to a relative density of about 1.28 (60°C), dried under reduced pressure at 60-80°C for 20 hours, and crushed into 80-mesh fine powder; (3) Add 5% microcrystalline cellulose to the fine powder , mixed evenly, granulated with a 14-mesh sieve, dried at 70°C for 4 hours, granulated with a 16-mesh, added with 0.5% magnesium stearate, and mixed evenly to obtain mixed granules; (4) Compress the mixed granules into tablets with a tablet machine , film-coated to obtain the tablet medicine of the present invention.

Embodiment 2

[0040] (1) Take 50 parts of medicinal materials Tianzicao, 40 parts of Yinxingcao, 40 parts of sorrel, 15 parts of Schisandra chinensis, and 15 parts of Yinchen. Decoct 10 times the amount of water twice, 2 hours each time, combine the decoction, filter, and the filtrate is separated and purified by adsorption on a macroporous adsorption resin column, and eluted with 70% ethanol until the eluate is nearly colorless, and the eluate is collected liquid, recovered ethanol, concentrated to a relative density of 1.30, dried under reduced pressure at 60-70°C for 18 hours, and crushed into 100-mesh fine powder A; Schisandra and capillary were extracted with 70% ethanol for 3 hours, and the extract was concentrated to a relative density of 1.30 (60°C), add 10% starch, dry under reduced pressure at 70°C for 25 hours, and pulverize into 100-mesh fine powder B; (3) Mix fine powder A and fine powder B, add 20% dextrin, and mix well , granulate with a 14 mesh sieve, dry at 75°C for 5 hours...

Embodiment 3

[0042] (1) Take 15 parts of medicinal materials Tianzicao, 20 parts of Yin Xingcao, and 20 parts of sorrel, cut and dry the medicinal materials after cleaning; (2) add 10 times the amount of water to decoct twice, each time for 2 hours, and fry together After the filtrate is absorbed by the adsorption resin, it is eluted with 70% ethanol until the eluate is nearly colorless, and the eluate is concentrated at 70-80°C to a relative density of about 1.28 (60°C), and then reduced at 60-70°C. Press and dry for 25 hours, crush into 60-mesh fine powder; (3) Add 10% calcium sulfate to the fine powder, mix well, granulate with 14-mesh sieve, dry at 60°C for 4 hours, granulate with 16-mesh, add 2% talc powder, and mixed to obtain mixed granules; (4) filling the mixed granules into capsules to obtain the capsule drug of the present invention.

[0043] The beneficial effect of the present invention will be further illustrated by the experimental examples below, and these experimental exam...

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PUM

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Abstract

The present invention discloses one kind of hepatitis treating Chinese medicine preparation and its preparation process. The hepatitis treating Chinese medicine preparation is prepared with clover fern, Yinxingcao and garden sorrel as main material as well as schisandra and capillary artemisia. The present invention has reasonable preparation process, has most of its impurity eliminated and effective component concentrated via extraction, separation and purification, and the medicine product has improved moistureproof property, stable and controllable quality and obvious curative effect.

Description

[technical field] [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating hepatitis and a preparation method thereof. [Background technique] [0002] Hepatitis is a common infectious disease that spreads among a wide range of people and has spread in many countries and races. It is one of the major contemporary infectious diseases. Western medicine pathology thinks it is a kind of inflammation, so it is called hepatitis, and it is divided into type A and type B. Sometimes it is called viral hepatitis and icteric hepatitis according to its clinical manifestations, or it is called acute according to the priority of its onset. Hepatitis, chronic hepatitis. At present, the main medicines for treating hepatitis in Western medicine are antibacterial and antiviral drugs, but practice shows that the therapeutic effect is not very good. In our country, the combination of traditional Chinese medicine an...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61P1/16A61P31/14
Inventor 俞凯
Owner 四川泰华堂制药有限公司
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