Production process of microporous carbon hydroxyapatite

Abstract

The present invention process of microporous carbon hydroxyapatite with natural rock phosphate as material includes dissolving and eliminating impurity; compounding homogeneous Ca, P, urea and EDTA system; and foam inducing and homogeneous precipitation to obtain microporous carbon hydroxyapatite with pore size of 0.5-10 micron. The product has excellent organic and biological compatibity, ion exchange property, etc. as well as powerful protein separating, solid alkali catalysis, medicine carrying, radioactive substance solidifying and other capacity. It may be used in porous biological material, protein separation, chromatography, catalyst, catalyst carrier, medicine carrier, radioactive substance treatment and other fields.

Description

technical field [0001] The invention relates to a production method for preparing microporous carbon hydroxyapatite. Background technique [0002] At present, the known methods for preparing microporous hydroxyapatite include the following: 1. Animal hard tissue burning method; 2. Hard template pore-forming powder sintering method. Its characteristics are: ① High temperature sintering is required, above 600 ° C; ② The production raw materials used are chemical products and cannot use cheap natural phosphorite, so its production cost is high; ③ The pore size is too large, reaching more than 10 μm, which greatly affects limited its scope of application. Contents of the invention [0003] The purpose of the present invention is to overcome the defects and problems of the above-mentioned prior art, to provide a production method for microporous hydroxyapatite, which can make the microporous hydroxyapatite product be produced und...

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems of high sintering temperature above 600°C, expensive raw materials, and too large pore size in the production process of microporous hydroxyapatite, the technical solution is: select natural phosphorite, add acid to adjust pH = 4-6 Dissolve the phosphorite, subject to the complete dissolution of phosphorus and calcium, filter to remove insoluble impurities, the impurities are mainly quartz and clay, add appropriate amount of urea and ethylenediaminetetraacetic acid (EDTA) to the filtrate, put Make a homogeneous system in an autoclave, heat it to a temperature range of 90°C to 150°C, the urea will slowly hydrolyze to release hydroxyl groups and carbonates, and start to precipitate after reaching supersaturation, stop heating after reacting for 5 to 6 hours, and let it stand for 11 to 10 hours. After 13 hours, filter, granulate, and dry to obtain carba-hydroxyapatite mixed with carbonate groups in the pore size range of 0.5 μm to 10 μm

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