Method and device for producing fibrin glue and produced fibrin glue and its medical use

A fibrin and protein glue technology is applied in the production of fibrin glue and devices, the prepared fibrin glue and the fields of medical application thereof, and can solve the problems of ineffective surgical and clinical use.

Inactive Publication Date: 2006-08-23
梁华清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As mentioned above, cryoprecipitation requires prolonged freezing and thawing, making this method and device ineffective for surgical and clinical use

Method used

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  • Method and device for producing fibrin glue and produced fibrin glue and its medical use
  • Method and device for producing fibrin glue and produced fibrin glue and its medical use
  • Method and device for producing fibrin glue and produced fibrin glue and its medical use

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Experimental program
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Embodiment Construction

[0059] Best practice:

[0060] refer to figure 1 As shown, according to the technology of the present invention, the device 100 is used to produce fibrinogen with high concentration, high adhesive strength and high hemostatic effect.

[0061] The patient's blood is first drawn from the needle 102 . By action of the peristaltic pump 112, the blood is immediately mixed with the anticoagulant drawn from the plasma bag 114, which serves as a reservoir for the anticoagulant. The patient's blood is pumped to the reinfusion reservoir 106 through the peristaltic pump 104, and then transferred to the membrane or centrifuge device 110 through the peristaltic pump 108, where the automatic blood component transfusion process is performed. Red blood cells drawn from the patient's blood are transferred to the second plasma bag 116 through the automated blood component transfusion process, and then infused back into the patient. The plasma membrane separation device 110 may be a membrane ...

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PUM

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Abstract

The present invention relates to the technological process of producing fibrin glue with plasma. The fibrin glue is produced with plasma and through 8-10 times of fast freezing, repeated deposition and dissolving, and filtering separation to obtain the precipitate. The apparatus for the technological process is also provided, and it is one mixer with a thermostat and a double injector. The fibrin glue prepared through the technological process contains high concentration fibrinogen and no chemical precipitant, has high adhesion and high hemostatic effect, and may be used in preparing antithrombus film through combining with anticoagulant, with the antithrombus film being used in preventing recurrence of thrombus after cardiac catheter operation. The present invention also relates to one new kind of thrombolytic of sinomenine to dissolve and prevent thrombus in vein and artery without destructing the blood coagulation mechanism.

Description

[0001] This application is a divisional application with the filing date being May 10, 2000, the application number being 00108682.0, and the title of the invention being "A device for producing blood products such as fibrin glue and its medical application". technical field [0002] The present invention relates to a process and apparatus for preparing fibrinogen from blood plasma. In particular, it relates to a new device for the production of fibrin glue from plasma using a new manufacturing process. The preparation process can be carried out in a completely closed and aseptic system, so as to prevent the preparation from being exposed to air and polluted. In addition, the present invention also relates to a thermostatic double syringe, which is used to maintain the fibrin glue in a liquid state and mix it with thrombin to form a uniform liquid to obtain the effects of hemostasis and tissue adhesion. [0003] The invention also relates to a thrombus-dissolving agent tetran...

Claims

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Application Information

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IPC IPC(8): A61K35/16A61M5/00A61P7/02
Inventor 黄浔阳梁钢梁焰
Owner 梁华清
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