Chinese medicinal preparation for treating urinary system disease, its preparation method and quality control method

A technology for urological diseases and traditional Chinese medicine preparations, applied in the field of traditional Chinese medicine preparations and their preparation, can solve the problems of low bioavailability, unpleasant smell, inconvenience in carrying and taking, etc.

Inactive Publication Date: 2006-08-30
王衡新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing traditional Chinese medicine preparation for treating urinary system diseases, Jieshitong Tablet, has disadvantages such as inconvenient to carry and take, low bioavailability, and unpleasant smell.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 2

[0046] Take 316g each of Desmodium syringae, Chickengrass, and Imperata praecox, 210g each of Shiwei, Haijinsha, and Plantain, 158g Poria cocos, and 264g corn silk, add water to decoct twice, each time for 2 hours, combine the decoction, and filter , the filtrate is concentrated into a clear paste with a relative density of 1.19 to 1.20 (90° C.), dried, pulverized, 240 g of polyethylene glycol PEG6000, 80 g of stearic acid, and 45 g of Poloxamer188 are heated to After it is completely melted, add it to the above-mentioned fine powder of the drug, stir it evenly, and quickly transfer it to the liquid storage bottle, seal it and keep it warm at 80°C, drop it into the liquid paraffin from the dropping pill machine under the heat preservation condition, condense into pills, and put the formed Drain the dripping pills, wipe off the liquid paraffin, and dry at low temperature to obtain the Jieshitong dripping pills.

specific Embodiment 3

[0047] Take 316g each of Desmodium syringae, Chickengrass, and Imperata praecox, 210g each of Shiwei, Haijinsha, and Plantain, 158g Poria cocos, and 264g corn silk, add water to decoct twice, each time for 2 hours, combine the decoction, and filter , the filtrate is concentrated into a clear paste with a relative density of 1.19 to 1.20 (90° C.), dried, pulverized, 240 g of polyethylene glycol PEG6000, 80 g of stearic acid, and 45 g of Poloxamer188 are heated to After it is completely melted, add it to the above-mentioned fine powder of the drug, stir it evenly, and quickly transfer it to the liquid storage bottle, seal it and keep it warm at 80°C, drop it into the liquid paraffin from the dropping pill machine under the heat preservation condition, condense into pills, and put the formed The dripping pills are drained and the liquid paraffin is wiped off, dried at low temperature, and coated with a mixture of acrylic resin, diethyl phthalate, castor oil, etc.

specific Embodiment 4

[0048] Take 316g each of Desmodium syringae, Chickengrass, and Imperata praecox, 210g each of Shiwei, Haijinsha, and Plantain, 158g Poria cocos, and 264g corn silk, add water to decoct twice, each time for 2 hours, combine the decoction, and filter , the filtrate is concentrated into a clear paste with a relative density of 1.19 to 1.20 (90°C), dried, pulverized, mixed evenly with 350g of dextrin, and 5% PVP alcohol as a binder. 5% PVP alcohol solution is used as a binding agent, and the mixed medicinal powder is added to enlarge and make 40-mesh pellets, namely, Jieshitong pellets.

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Abstract

A Chinese medicine in the form of pill, dripping pill, tablet or soft capsule for treating the diseases in urinary system is prepared from 8 Chinese-medicinal materials including lysimachia, tuckahoe, plantain bark, imperate rhizome, etc through extracting in water, concentating, adding additives and shaping. Its quality control method is also disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating urinary system diseases, a preparation method and a quality control method thereof. Background technique: [0002] Pills or drop pills or enteric-coated drop pills or micropills or micropill capsules or dispersible tablets or soft capsules in traditional Chinese medicine preparations are used as a pharmaceutical dosage form. According to the relevant laws and regulations of drug management in my country, changes in dosage forms and processes are managed as new drug research. The current dosage form of this product is tablets, which has been included in the thirteenth volume of standards issued by the Ministry of Pharmaceuticals. Through patent search: 2002 disclosed a kind of nano-Jishitong preparation drug and its preparation method (publication number: CN1362163), no Jieshitong...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61K9/20A61K9/48A61P13/00
Inventor 王衡新
Owner 王衡新
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